Isosorbide Mononitrate Tablet, Extended Release
Pricing Report NDC 59651-539-05

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Isosorbide Mononitrate (NDC 59651-539-05) is $0.07505 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Aurobindo Pharma Limited, this medication is distributed in a 500 TABLET, EXTENDED RELEASE in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.07505
Per EA

Effective Date
Jun 17, 2026
Billable Units
500 EA
Estimated Package Price
$37.52
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
500 TABLET, EXTENDED RELEASE in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2023, the NADAC wholesale price for (NDC ) has moved within a range of $0.05820 to $0.08751 per EA. Over this 3 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0582 - $0.0875
Market Volatility
50.36% Variance
Latest Trend
0.07%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.07505 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 17, 2026 $0.07505 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $0.07510 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $0.07510 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $0.07285 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $0.07285 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $0.07064 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $0.07064 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $0.07002 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $0.07002 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $0.06990 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $0.06990 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $0.06958 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $0.06958 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $0.07003 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $0.07003 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $0.07056 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $0.07056 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $0.07145 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $0.07145 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $0.07319 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $0.07319 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $0.07322 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $0.07322 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $0.07385 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $0.07385 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $0.07300 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $0.07300 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $0.07276 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $0.07276 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $0.07349 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $0.07349 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $0.06993 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $0.06993 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $0.06531 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $0.06531 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $0.06616 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $0.06616 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $0.05820 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $0.05820 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $0.07851 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $0.07851 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $0.07770 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $0.07770 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $0.07785 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $0.07785 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $0.06148 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $0.06148 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $0.07495 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $0.07495 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $0.06535 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $0.06535 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $0.06632 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $0.06632 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 20, 2024 $0.08605 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 20, 2024 $0.08605 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 21, 2024 $0.08068 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 21, 2024 $0.08068 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 17, 2024 $0.08622 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 17, 2024 $0.08622 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 20, 2023 $0.08030 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 20, 2023 $0.08030 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 22, 2023 $0.07572 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 22, 2023 $0.07572 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 18, 2023 $0.07693 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 18, 2023 $0.07693 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 20, 2023 $0.08392 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 20, 2023 $0.08392 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $0.08325 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $0.08325 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 19, 2023 $0.08001 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 19, 2023 $0.08001 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 21, 2023 $0.07957 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 21, 2023 $0.07957 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2023 $0.08751 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2023 $0.08751 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 19, 2023 $0.08225 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 19, 2023 $0.08225 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 05, 2023 $0.08590 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 05, 2023 $0.08590 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026