Polymyxin B Sulfate And Trimethoprim Solution
Pricing Report NDC 61314-628-10

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Polymyxin B Sulfate And Trimethoprim (NDC 61314-628-10) is $0.45266 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Sandoz Inc, this medication is distributed in a 1 BOTTLE, PLASTIC in 1 CARTON / 10 mL in 1 BOTTLE, PLASTIC configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.45266
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 BOTTLE, PLASTIC in 1 CARTON / 10 mL in 1 BOTTLE, PLASTIC
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2013, the NADAC wholesale price for (NDC ) has moved within a range of $0.37957 to $0.86781 per ML. Over this 12 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.3796 - $0.8678
Market Volatility
128.63% Variance
Latest Trend
0.22%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.45266 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.45364 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.45326 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.45883 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.46396 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.47321 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.47554 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.47085 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.46879 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.47143 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.47440 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.47191 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.46925 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.47498 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.48097 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.48670 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.46083 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.43544 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.44777 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.40443 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.53452 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.55582 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.52126 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.43691 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.44372 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.37957 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.39626 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $0.46411 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $0.44114 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $0.45592 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.44744 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $0.47205 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $0.48111 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2023 $0.53682 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $0.49426 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $0.52103 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $0.54168 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $0.50901 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $0.49475 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $0.48993 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $0.43683 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $0.43477 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $0.41077 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $0.43542 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $0.44394 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2022 $0.58255 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $0.55851 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2022 $0.51276 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $0.45670 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $0.51899 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $0.45550 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $0.46086 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $0.45508 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 19, 2022 $0.44839 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $0.45534 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 17, 2021 $0.48459 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $0.47170 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $0.47306 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $0.47790 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 21, 2021 $0.50034 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 23, 2021 $0.48537 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 19, 2021 $0.44757 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 21, 2021 $0.44429 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 17, 2021 $0.49458 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 17, 2021 $0.48427 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 20, 2021 $0.49776 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2020 $0.50332 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 18, 2020 $0.46339 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 21, 2020 $0.52683 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 23, 2020 $0.50299 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2020 $0.52186 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2020 $0.46291 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2020 $0.51540 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2020 $0.54293 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2020 $0.52867 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2020 $0.55969 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2020 $0.53040 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2020 $0.53224 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2019 $0.55391 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2019 $0.56002 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2019 $0.53897 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2019 $0.53195 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2019 $0.63575 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2019 $0.51216 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2019 $0.55594 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2019 $0.55583 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2019 $0.50551 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2019 $0.48797 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 20, 2019 $0.48357 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 23, 2019 $0.50385 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 19, 2018 $0.52802 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 21, 2018 $0.53942 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 17, 2018 $0.48646 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 19, 2018 $0.53669 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 22, 2018 $0.54946 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 18, 2018 $0.52365 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 20, 2018 $0.52638 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 23, 2018 $0.54944 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 18, 2018 $0.54648 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 21, 2018 $0.56226 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2018 $0.59175 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2018 $0.56048 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2017 $0.54207 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2017 $0.59731 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2017 $0.57709 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2017 $0.60750 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2017 $0.61877 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2017 $0.58071 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2017 $0.57442 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2017 $0.57409 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2017 $0.55891 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2017 $0.56010 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2017 $0.61186 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2017 $0.56017 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2016 $0.64017 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2016 $0.65607 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2016 $0.65367 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2016 $0.62757 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2016 $0.68652 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2016 $0.65667 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2016 $0.61854 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2016 $0.66516 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2016 $0.69473 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2016 $0.73030 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 17, 2016 $0.63122 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 20, 2016 $0.66784 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2015 $0.69891 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 18, 2015 $0.61091 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 21, 2015 $0.63842 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 23, 2015 $0.64119 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2015 $0.63151 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2015 $0.75599 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2015 $0.78133 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2015 $0.74286 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2015 $0.78367 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2015 $0.80895 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2015 $0.81823 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2015 $0.73789 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2014 $0.73566 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2014 $0.73817 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2014 $0.75532 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2014 $0.82229 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2014 $0.84098 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2014 $0.86781 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2014 $0.83736 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2014 $0.80243 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2014 $0.80025 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2014 $0.81584 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2014 $0.82322 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2014 $0.81037 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2013 $0.78412 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 21, 2013 $0.73471 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026