Boxed Warning (Diclo575boxedwarning)
This text discusses the risks associated with Nonsteroidal anti-inflammatory drugs (NSAIDs), including an increased risk of cardiovascular thrombotic events such as heart attack and stroke, as well as serious gastrointestinal adverse events such as inflammation, bleeding, ulceration, and perforation of the stomach or intestines which can be fatal. The risk of these events may occur early in treatment and increase with duration of use. Elderly patients have a higher risk of serious gastrointestinal events. Additionally, Diclofenac sodium delayed-release tablets are contraindicated in the setting of coronary artery bypass graft (CABG) surgery.*