B21 Spray
NDC Package 63479-0221-1

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

B21 (aconitum napellus, apis mellifica, arnica montana, arsenicum album, belladonna, bellis perennis, bryonia, calendula officinalis, chamomilla, cherry plum, clematis vitalba, colocynthis, comfrey, dulcamara lignosa, echinacea angustifolia, echinacea purpurea, eupatorium perfoliatum, ferrum phosphoricum, hamamelis virginiana, histaminum, hypericum perforatum, impatiens glandulifera, ledum palustre, mentha piperita, millefolium, ornithogalum umbellatum, plantago major, rhus toxicodendron, rockrose, sulphur, veratrum album, verbascum thapsus) sprays is adults & children ages 12 years and over: Take 2-3 sprays orally, or topically as directed by your healthcare professional. This formulation utilizes a spray delivery system. Marketed by Apex Energetics Inc., this product is identified by NDC 63479-0221.

Identification & Billing

NDC Package Code
63479-0221-1
Package Description
60 mL in 1 BOTTLE, SPRAY
Product Code
63479-0221
11-Digit Billing Format
63479022101

Clinical Specifications

Proprietary Name
B21 Acute Rescue
Non-Proprietary Name
Aconitum Napellus, Apis Mellifica, Arnica Montana, Arsenicum Album, Belladonna, Bellis Perennis, Bryonia, Calendula Officinalis, Chamomilla, Cherry Plum, Clematis Vitalba, Colocynthis, Comfrey, Dulcamara Lignosa, Echinacea Angustifolia, Echinacea Purpurea, Eupatorium Perfoliatum, Ferrum Phosphoricum, Hamamelis Virginiana, Histaminum, Hypericum Perforatum, Impatiens Glandulifera, Ledum Palustre, Mentha Piperita, Millefolium, Ornithogalum Umbellatum, Plantago Major, Rhus Toxicodendron, Rockrose, Sulphur, Veratrum Album, Verbascum Thapsus
Substance Name
Apis Mellifera; Arnica Montana; Atropa Belladonna; Bryonia Alba Root; Prunus Cerasifera Flower; Citrullus Colocynthis Fruit Pulp; Echinacea Purpurea; Echinacea Angustifolia; Ledum Palustre Twig; Mentha Piperita; Plantago Major; Ornithogalum Umbellatum Flowering Top; Toxicodendron Pubescens Leaf; Helianthemum Nummularium Flower; Histamine Dihydrochloride; Sulfur; Comfrey Root; Veratrum Album Root; Verbascum Thapsus; Arsenic Trioxide; Bellis Perennis; Calendula Officinalis Flowering Top; Matricaria Chamomilla Whole; Eupatorium Perfoliatum Flowering Top; Ferrosoferric Phosphate; Hamamelis Virginiana Root Bark/stem Bark; Hypericum Perforatum; Impatiens Glandulifera Flower; Achillea Millefolium; Aconitum Napellus; Clematis Vitalba Flower; Solanum Dulcamara Whole
Dosage Form
Spray - A liquid minutely divided as by a jet of air or steam.
Administration Route
Sublingual - Administration beneath the tongue.
Active Ingredient(s)
Pharmacologic Class
Usage Information
Adults & children ages 12 years and over: Take 2-3 sprays orally, or topically as directed by your healthcare professional. Consult a physician for use in children under 12 years of age.

Regulatory & Marketing

Labeler Name
Apex Energetics Inc.
Product Type
Human Otc Drug
Marketing Category
UNAPPROVED HOMEOPATHIC - A category specifying that a product is marketed as unapproved homeopathic product.
Start Marketing Date
05-15-2024
Listing Expiration
12-31-2026
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 63479-0221-1 identifies a specific commercial package of 60 ml in 1 bottle, spray of B21 Acute Rescue, a human over the counter drug labeled by Apex Energetics Inc.. This spray is formulated for sublingual use and contains apis mellifera; arnica montana; atropa belladonna; bryonia alba root; prunus cerasifera flower; citrullus colocynthis fruit pulp; echinacea purpurea; echinacea angustifolia; ledum palustre twig; mentha piperita; plantago major; ornithogalum umbellatum flowering top; toxicodendron pubescens leaf; helianthemum nummularium flower; histamine dihydrochloride; sulfur; comfrey root; veratrum album root; verbascum thapsus; arsenic trioxide; bellis perennis; calendula officinalis flowering top; matricaria chamomilla whole; eupatorium perfoliatum flowering top; ferrosoferric phosphate; hamamelis virginiana root bark/stem bark; hypericum perforatum; impatiens glandulifera flower; achillea millefolium; aconitum napellus; clematis vitalba flower; solanum dulcamara whole as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Apex Energetics Inc. on May 15, 2024. The current certification is valid through December 31, 2026.

How is this Apex Energetics Inc. product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 63479022101. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-4-1)
63479-0221-1
11-Digit CMS (5-4-2)
63479-0221-01

Note: The zero is added to the Package segment to maintain the 5-4-2 structure.