Apriso Capsule, Extended Release
Pricing Report NDC 65649-103-02

Latest NADAC: $4.07102 per EA · Effective Sep 17, 2025 · Est. package price $488.52 (120 EA)
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The latest wholesale acquisition cost for Apriso (NDC 65649-103-02) is $4.07102 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Sep 17, 2025.

As a a human prescription drug provided by Salix Pharmaceuticals, Inc., this medication is distributed in a 1 BOTTLE in 1 CARTON / 120 CAPSULE, EXTENDED RELEASE in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$4.07102
Per EA

Pricing Unit
Per EA Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Sep 17, 2025
Billable Units
120 EA
Estimated Package Price
$488.52
Data Status
As of Oct 01, 2025
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
B - Brand
Package NDC
65649-103-02
Description
1 BOTTLE in 1 CARTON / 120 CAPSULE, EXTENDED RELEASE in 1 BOTTLE
Generic Benchmark
The generic equivalent rate is $0.45786 (Effective: Sep 17, 2025)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jun 2013, the NADAC wholesale price for (NDC ) has moved within a range of $2.58536 to $4.20289 per EA. Over this 12 years and 3 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.5854 - $4.2029
Market Volatility
62.56% Variance
Latest Trend
0.02%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Sep 17, 2025 $4.07102 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Aug 20, 2025 $4.07198 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jul 23, 2025 $4.07234 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jun 18, 2025 $4.07275 EAC/I - Chain or Independent PharmacyCode 1B - Brand
May 21, 2025 $4.07230 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Apr 23, 2025 $4.07213 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Mar 19, 2025 $4.07323 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Feb 19, 2025 $4.07506 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jan 22, 2025 $4.07514 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Dec 18, 2024 $4.07580 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Nov 20, 2024 $4.07472 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Oct 23, 2024 $4.07497 EAC/I - Chain or Independent PharmacyCode 1B - Brand

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: October 07, 2026