Relistor Injection, Solution
Pricing Report NDC 65649-551-02
View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Current Package Pricing Information
The latest wholesale acquisition cost for Relistor (NDC 65649-551-02) is $271.58333 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Sep 17, 2025.
As a a human prescription drug provided by Salix Pharmaceuticals, Inc., this medication is distributed in a 1 VIAL, SINGLE-DOSE in 1 CARTON / .6 mL in 1 VIAL, SINGLE-DOSE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.
NADAC Pricing Summary
NADAC pricing snapshot for this package NDC
Acquisition Cost $271.58333 Per ML
Pricing Unit
Effective Date
Sep 17, 2025
Data Status
As of Oct 01, 2025
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The NADAC was calculated based on package size.
Historical Pricing Trends & Acquisition Cost Benchmarks
Since Jun 2013, the NADAC wholesale price for (NDC ) has moved within a range of $95.90670 to $272.89428 per ML. Over this 12 years and 3 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.
Price Range
$96.6422 - $272.5976
$96.6422 - $272.5976
Market Volatility
182.07% Variance
182.07% Variance
Latest Trend
No Change
No Change
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Sep 17, 2025 | $271.58333 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Sep 17, 2025 | $272.68301 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 20, 2025 | $271.58333 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 20, 2025 | $272.89428 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 23, 2025 | $272.59762 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 18, 2025 | $271.86190 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 21, 2025 | $272.04683 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 01, 2025 | $270.32243 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 01, 2025 | $270.32243 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2025 | $270.32243 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 01, 2025 | $271.48457 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 01, 2025 | $271.48457 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2025 | $271.48457 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 01, 2025 | $271.20735 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 01, 2025 | $271.20735 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2025 | $271.20735 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Dec 18, 2024 | $255.01875 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 18, 2024 | $256.11752 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 18, 2024 | $255.85357 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 20, 2024 | $255.47381 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 20, 2024 | $256.07721 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 20, 2024 | $255.87564 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 23, 2024 | $256.07619 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 23, 2024 | $255.96250 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Sep 18, 2024 | $255.53244 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Sep 18, 2024 | $255.84091 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 21, 2024 | $255.65952 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 21, 2024 | $255.98889 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 17, 2024 | $255.37179 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 17, 2024 | $256.12500 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 19, 2024 | $256.09026 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 19, 2024 | $255.41111 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 22, 2024 | $256.27823 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 01, 2024 | $254.65809 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2024 | $254.65809 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 01, 2024 | $256.46842 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2024 | $256.46842 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 01, 2023 | $244.39591 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2023 | $244.39591 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 01, 2023 | $246.13092 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 01, 2023 | $246.13092 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2023 | $246.13092 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Dec 21, 2022 | $230.56000 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 01, 2022 | $232.19898 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2022 | $232.19898 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 01, 2021 | $215.19831 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 01, 2021 | $215.19831 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2021 | $215.19831 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 09, 2020 | $199.44236 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 09, 2020 | $199.44236 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 09, 2020 | $199.44236 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| May 22, 2019 | $184.84000 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 22, 2019 | $184.84000 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Oct 05, 2017 | $174.20313 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Oct 05, 2017 | $174.20313 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Oct 05, 2017 | $174.20313 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| May 17, 2017 | $159.81939 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 17, 2017 | $159.81939 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| May 17, 2017 | $159.81939 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Oct 19, 2016 | $163.06701 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 19, 2016 | $163.06701 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Oct 19, 2016 | $163.06701 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 22, 2016 | $159.26364 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 22, 2016 | $159.26364 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| May 18, 2016 | $160.00278 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 18, 2016 | $160.00278 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Sep 11, 2015 | $159.43609 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Sep 11, 2015 | $159.43609 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Sep 11, 2015 | $159.43609 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Sep 11, 2015 | $162.28121 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Sep 11, 2015 | $162.28121 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 31, 2015 | $114.88985 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 31, 2015 | $114.88985 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 31, 2015 | $114.88985 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 31, 2015 | $116.94341 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 31, 2015 | $116.94341 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 31, 2015 | $116.94341 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Nov 19, 2014 | $104.44722 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 19, 2014 | $104.44722 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 03, 2014 | $107.35217 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jun 03, 2014 | $107.35217 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 03, 2014 | $106.31413 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jun 03, 2014 | $106.31413 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| May 21, 2014 | $96.64218 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 14, 2013 | $97.58579 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jun 14, 2013 | $97.58579 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 14, 2013 | $95.90670 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jun 14, 2013 | $95.90670 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
Pricing Methodology Legend
- Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
- Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
- Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
- Code 4: The NADAC was carried forward from the previous file.
- Code 5: The NADAC was calculated based on package size.
Understanding NADAC Pricing Data
The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.
Important Price Distinction:
The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.
NADAC Pricing Data Last Updated on: July 08, 2026
