Kristalose Powder, For Solution
Pricing Report NDC 66220-729-30

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Kristalose (NDC 66220-729-30) is $9.94822 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Cumberland Pharmaceuticals Inc., this medication is distributed in a 30 POUCH in 1 CARTON / 20 g in 1 POUCH (66220-729-01) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$9.94822
Per EA

Effective Date
Jun 17, 2026
Billable Units
1 EA
Estimated Package Price
$9.95
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
B-ANDA - Abbreviated New Drug Application
Package NDC
Description
30 POUCH in 1 CARTON / 20 g in 1 POUCH (66220-729-01)
Generic Benchmark
The generic equivalent rate is $7.97999 (Effective: Jun 17, 2026)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2013, the NADAC wholesale price for (NDC ) has moved within a range of $2.63296 to $9.97702 per EA. Over this 12 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.6330 - $9.9770
Market Volatility
278.93% Variance
Latest Trend
No Change
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $9.94822 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
May 20, 2026 $9.94822 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2026 $9.97702 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2026 $9.97702 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2026 $9.97702 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2026 $9.97702 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2026 $9.97702 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Dec 17, 2025 $9.73340 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Nov 19, 2025 $9.74005 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Oct 22, 2025 $9.74443 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Sep 17, 2025 $9.77110 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Aug 20, 2025 $9.75426 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jul 23, 2025 $9.75468 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jun 18, 2025 $9.74837 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
May 21, 2025 $9.74628 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Dec 23, 2024 $9.75397 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Dec 23, 2024 $9.75397 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Dec 23, 2024 $9.75397 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Dec 18, 2024 $9.47006 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Nov 20, 2024 $9.46070 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jun 28, 2024 $9.46263 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jun 28, 2024 $9.46263 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jun 28, 2024 $9.46263 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jun 19, 2024 $9.18702 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
May 22, 2024 $9.18686 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jan 03, 2024 $9.22369 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 03, 2024 $9.22369 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 03, 2024 $9.22369 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 19, 2023 $8.28980 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jul 19, 2023 $8.28980 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jul 19, 2023 $8.28980 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 05, 2023 $8.95504 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jul 05, 2023 $8.95504 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jul 05, 2023 $8.95504 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 20, 2022 $8.36920 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jul 20, 2022 $8.36920 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jul 20, 2022 $8.36920 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 14, 2021 $8.33434 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Oct 14, 2021 $8.33434 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 21, 2021 $8.09082 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 21, 2021 $8.09082 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 21, 2021 $8.09082 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 21, 2020 $7.70576 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Oct 21, 2020 $7.70576 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 03, 2020 $7.69970 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 03, 2020 $7.69970 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 03, 2020 $7.69970 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Nov 20, 2019 $7.33318 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Nov 20, 2019 $7.33318 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 31, 2019 $7.31092 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 31, 2019 $7.31092 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 31, 2019 $7.31092 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Sep 06, 2018 $7.02973 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Sep 06, 2018 $7.02973 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Sep 06, 2018 $7.02973 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Aug 22, 2018 $6.69498 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Nov 22, 2017 $6.73485 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Nov 22, 2017 $6.73485 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Feb 22, 2017 $6.72274 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Feb 22, 2017 $6.72274 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 05, 2017 $6.71777 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
May 19, 2016 $6.39787 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
May 19, 2016 $6.39787 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Dec 23, 2015 $6.26800 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Dec 23, 2015 $6.26800 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Mar 18, 2015 $6.27825 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Mar 18, 2015 $6.27825 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 15, 2015 $6.31840 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 15, 2015 $6.31840 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2014 $5.90494 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2014 $5.90494 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Feb 19, 2014 $5.92692 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 13, 2014 $5.91986 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Nov 21, 2013 $2.63296 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Nov 21, 2013 $2.63296 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026