Chlorhexidine Gluconate Rinse
Product Images NDC 66467-2560

This is a description of an oral rinse manufactured by Darby Dental Supply. The rinse consists of chlorhexidine gluconate, sodium saccharin, FD&C Blue No. 1, and flavoring in a base containing 11.6% alcohol, glycerin, and PEG-40 sorbitan diisostearate. The rinse is mint flavored and should be used undiluted, swishing 1 tablespoon (15 mL) in the mouth for 30 seconds and then spit out. The rinse should be used after breakfast and before bedtime or as prescribed. After use, water should not be rinsed immediately to minimize the medicinal taste. The product is only available through prescription and should be kept out of reach of children. The container holds 4 oz. (118 mL) and the NDC number is 66467-2560-4.*

This is a description of a mouth rinse called 0.12% chlorhexidine gluconate (CHG) that contains 1,11-hexamethylene bis [5-(p-chlorophenyl) biguanide] di-D-gluconate, alcohol, glycerin, flavor, and other ingredients. It is a neutral solution that has antimicrobial activity and reduces the count of certain bacteria in the mouth, without causing any significant changes in bacterial resistance, overgrowth of potentially opportunistic organisms or other adverse changes in the oral microbial ecosystem. Studies indicate that approximately 30% of the active ingredient is absorbed from the oral cavity.*

Chlorhexidine gluconate is a drug that is slowly released into the oral fluids and is poorly absorbed from the gastrointestinal tract. It is primarily excreted through the feces and has not been tested among patients with acute necrotizing ulcerative gingivitis (ANUG). It should not be used by persons who are hypersensitive to chlorhexidine gluconate or its ingredients. The effect of chlorhexidine gluconate oral rinse on periodontitis has not been determined, and its use may result in an increase in supragingival calculus. Anaphylaxis and serious allergic reactions have been reported during postmarketing use with dental products containing chlorhexidine.*

This text provides precautions related to the use of chlorhexidine gluconate oral rinse. It highlights that the use of gingival inflammation as an indicator of underlying periodontitis may not be accurate, and that the rinse may cause staining of oral surfaces. Patients with heavier accumulations of unremoved plaque may experience more pronounced staining, but it does not adversely affect oral health. Discretion is recommended when prescribing the rinse to patients with anterior facial restorations with rough surfaces or margins. The text notes that some patients may experience an alteration in taste perception during the treatment, and rare instances of permanent taste alteration have been reported.*

Chlorhexidine gluconate is a drug used as an oral rinse to treat gingivitis and other oral infections. Animal studies have not revealed evidence of harm to the fetus, but there have not been adequate and well-controlled studies in pregnant women, thus this drug should be used during pregnancy only if clearly necessary. It is not known whether the drug is excreted in human milk, so caution should be exercised when it is administered to nursing women. Clinical effectiveness and safety have not been established in children under the age of 18. The most common side effects are an increase in staining of teeth and other oral surfaces and an increase in calculus. No evidence of impaired fertility was observed in rats at doses up to 100 mg/kg/day.*

This text provides information on the possible side effects, overdosage, dosage, and administration of chlorhexidine gluconate oral rinse, a medication used for dental prophylaxis. The text warns of oral irritation and local allergy-type symptoms as potential side effects and mentions several reported oral mucosal side effects, including stomatitis, gingivitis, and ulcer. The text also cautions that ingestion of more than 4 ounces of the oral rinse by a small child or signs of alcohol intoxication require medical attention. Finally, the text recommends the use of the medication twice daily after tooth brushing, with prophylaxis recommended no less than every six months.*

This text provides instructions for the usage and storage of chlorhexidine gluconate oral rinse, a common medication used to treat oral health issues. The usual dosage and administration of the medication is described, including warnings against immediate brushing or eating following use. The supplied packaging and storage requirements are also detailed in the text.*

Your dentist may prescribe Chlorhexidine Gluconate Oral Rinse to treat gingivitis, reduce redness and swelling of gums, and control gum bleeding. Regular use as directed by your dentist, in addition to daily brushing, is recommended. Chlorhexidine Gluconate Oral Rinse should not be swallowed and may cause tooth discoloration or increase tartar formation. You may experience a bitter taste and food taste changes with its use. If any allergic symptoms develop, seek medical attention immediately. It should not be used by people with sensitivity to it or its components. Contact your dentist, pharmacist or call 1-800-361-2862 for any questions or concerns. STORE it between 20°C to 25°C (68°F to 77°F).*

This is a description of an oral rinse by Darby Dental Supply. The rinse is made of Chlorhexidine Gluconate and is 0.12% mint flavored. The prescription bottle contains 1 pint (473mL) and can either be dispensed from the bottle provided or an amber glass. It is for professional use only and should be kept away from the reach of children. The directions are to fill the cap to the fill line with 15mL of rinse and swish it in the mouth undiluted for 30 seconds, then spit it out. The oral rinse should be used after breakfast and before bedtime or as prescribed by a dentist. It is advised to not rinse with water immediately after use to minimize medicinal taste.*

Chlorhexidine Gluconate Oral Rinse is a dentist-prescribed medication used to cure gingivitis, control gum bleeding and decrease gum redness and swelling. It includes glycerin, alcohol, flavor, PEG-40 Sorbitan Diisostearate, 0.12% Chlorhexidine gluconate, Lift Sodium Saccharin and FD&C Blue No.1. The rinse must not be swallowed and it should be spat out. The rinse can cause tartar formation and permanent discoloration of front-tooth fillings. One should brush and floss regularly. Chlorhexidine Gluconate Oral Rinse can taste bitter and result in changes in taste. Store at room temperature, 1 pint (473 mL). If you have any questions, contact your pharmacist, dentist or call their toll-free number.*

Chlorhexidine Gluconate Oral Rinse is a prescription drug that helps reduce gingivitis, redness, swelling, and gum bleeding. It contains chlorhexidine gluconate, alcohol, glycerin, PEG-40 sorbitan diisostearate, flavor, sodium saccharin, and FD&C Blue No. 1. To open the cap, squeeze the smooth areas near the bottom and turn. To close, turn the cap until it locks. Use as directed by the dentist in addition to daily brushing, and do not swallow. Allergic reactions such as skin rash, itch, and difficulty breathing require medical attention immediately. Chlorhexidine gluconate oral rinse may cause tooth discoloration and increase tartar formation. Brushing and flossing daily will minimize discoloration. The rinse may taste bitter, causing interference in food and beverage tasting; hence rinse with it after meals. Contact the dentist, pharmacist or call toll-free number for queries or complaints. Store between 68°F to 77°F (20°C to 25°C), with permitted excursions of 59°F to 86°F (15°C to 30°C).*

This is a description of a chlorhexidine gluconate oral rinse, which is prescribed for patients having gingivitis characterized by redness, swelling of the gingivae, and bleeding upon probing. The oral rinse contains 0.12% chlorhexidine gluconate in a near-neutral solution and provides antimicrobial activity for six months. Pharmacokinetic studies indicate that approximately 30% of the active ingredient is retained in the oral cavity following rinsing, which is slowly released in the oral fluids. Chlorhexidine gluconate oral rinse is poorly absorbed from the gastrointestinal tract, and excretion occurs primarily through the feces (~90%). Chlorhexidine gluconate oral rinse has not been tested among patients with acute necrotizing ulcerative gingivitis (ANUG).*

Chlorhexidine gluconate oral rinse is a medication that should not be used by individuals who are hypersensitive to any of the ingredients. It is uncertain if the medication has an impact on periodontitis. In clinical testing, an increase in supragingival calculus was observed in users of Chlorhexidine gluconate oral rinse in comparison to control users. It cannot be established if Chlorhexidine gluconate oral rinse use leads to an increase in subgingival calculus. Patients should get a dental prophylaxis to remove calculus not exceeding six months. Patients have to be wary of anaphylaxis and serious allergic reactions that might occur after dental products containing Chlorhexidine are used. Patients' gingival inflammation following Chlorhexidine gluconate oral rinse treatment should not be used as the key indicator of underlying periodontitis. Chlorhexidine gluconate oral rinse can stain surfaces of the teeth, tooth restorations, and the tongue dorsum. Not all patients will exhibit visually significant tooth staining. Dental professionals and patients should exercise discretion when calcium deposits accumulate on dental restorations with rough margins or surfaces. Patients who cannot remove natural stain by a dental prophylaxis should not use Chlorhexidine gluconate oral rinse if permanent discolouration is unacceptable. Any changes in taste buds experienced by patients should be reported to dental professionals. Chlorhexidine gluconate oral rinse may pose a risk to pregnant and nursing women. A caution should also be exercised when Chlorhexidine gluconate oral rinse is given to nursing women. However, it is not clear if Chlorhexidine gluconate oral rinse is present in human milk. The application of Chlorhexidine gluconate in rats and rabbits did not demonstrate evidence of fetal harm.*

Chlorhexidine gluconate oral rinse is not recommended for children under the age of 18 due to the lack of established clinical effectiveness and safety. Studies have shown no found no evidence of carcinogenic or mutagenic effects in mammals, and it hasn't impeded fertility. Common side effects of the rinse include staining of teeth, calculus formation, and changes in taste perception. Minor irritation of the oral mucosa has also been noted. Overdosing on the rinse may cause discomfort or intoxication, and patients should use it twice a day for 30 seconds, do not rinse with water, eat, or brush teeth after using it. It is supplied to patients as a blue liquid in 1-pint (473 mL) amber plastic bottles with child-resistant dispensing closures.*