Naloxone Hydrochloride
Pricing Report NDC 67457-645-02

Current NADAC: $4.01468 per ML · Effective Aug 19, 2026
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

This product is EXCLUDED from the official NDC directory because the listing data was discontinued by the firm.

The current wholesale acquisition cost for Naloxone Hydrochloride (NDC 67457-645-02) is $4.01468 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 19, 2026.

As a provided by Mylan Institutional Llc, this medication is distributed in a 10 VIAL, SINGLE-DOSE in 1 CARTON / 1 mL in 1 VIAL, SINGLE-DOSE (67457-645-00) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$4.01468
Per ML

Pricing Unit
Per ML Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Aug 19, 2026
Data Status
As of Aug 19, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
67457-645-02
Description
10 VIAL, SINGLE-DOSE in 1 CARTON / 1 mL in 1 VIAL, SINGLE-DOSE (67457-645-00)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since May 2021, the NADAC wholesale price for (NDC ) has moved within a range of $3.81717 to $11.20940 per ML. Over this 5 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$3.8172 - $11.2094
Market Volatility
193.66% Variance
Latest Trend
5.05%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 19, 2026 $4.01468 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2026 $4.22833 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $4.41350 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $4.37712 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $4.25868 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $4.08955 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $3.95157 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $3.84465 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $3.81717 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $3.86703 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $4.18946 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $4.81880 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026