Product Images Venlafaxine Hydrochloride

This is a drug interaction table that provides information about the effects of certain drugs (Ethanol, Diazepam, Cimetidine, Ketoconazole, Indinavir, Metoprolol, Imipramine, and Lithium) on the activity of the liver enzyme CYP2D6. The table also shows the effects of these drugs on the blood levels of venlafaxine, and provides PK Fold Change and 90% C recommendations for these drugs. Clinical significance is unknown for some of these drugs, and caution is recommended when using them in patients with hypertension, elderly, or hepatic dysfunction. No dose adjustment is necessary for some drugs.*

This text appears to be a list of drugs and their interactions with other drugs. The drugs listed include ethanol, diazepam, alprazolam, indinavir, metoprolol, risperidone, imipramine, haloperidol, caffeine, and lithium. The text provides information on the PKFold change and the 90% C recommendation for these drugs. The text also includes information on whether concomitant use is recommended, whether there is a need for dose adjustment or cautionary use, and clinical significance for each drug, with some details on active moieties.*

This is a clinical pharmacology report discussing the effects of various conditions on the metabolization and recommended dosing of the drug venlafaxine. Factors discussed include liver and kidney impairment, age, gender, and genetic variations in metabolism. The report provides fold change and 90% confidence intervals for recommended dose adjustment in different scenarios.*