Estradiol Patch
Product Images NDC 68382-328

Product Visual Gallery

This gallery contains 17 technical images submitted to the FDA as part of the official labeling for Estradiol (NDC 68382-328). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.

As provided by Zydus Pharmaceuticals Usa Inc., these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 01)

Chemical structure of estradiol, showing its steroid core with hydroxyl groups and methyl substitution.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 02)

An illustration showing the layered construction of an estradiol transdermal patch. The layers from top to bottom include protective film, film backing, drug/adhesive layer, protective liner, and another protective film.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 03)

A line graph showing estradiol concentrations (pg/mL) over time (hours) for two estradiol transdermal patches at strengths of 0.025 mg/day and 0.05 mg/day. Concentrations peak around 20-50 pg/mL within 24-48 hours, with gradual decline through 180 hours. The 0.05 mg/day patch maintains higher concentrations throughout.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 04)

A line graph showing mean estradiol concentration (pg/mL) over time (hours) after transdermal estradiol patch application. Two curves compare concentration levels between buttock and abdomen application sites. The graph includes sampling times and error bars indicating variability.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 05)

A line graph showing percent change over time from baseline to 24 months in response to different estradiol patch dosages and placebo. The x-axis represents visit times at baseline, 6, 12, 18, and 24 months; the y-axis shows percent change from -5 to 6%. Lines represent placebo and daily doses of 0.025 mg, 0.05 mg, 0.06 mg, and 0.1 mg estradiol patches, with higher doses generally showing increased positive percent change compared to placebo.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 06)

A line graph showing the percent change over time from baseline to 24 months across different estradiol patch daily doses (0.025 mg, 0.05 mg, 0.06 mg, 0.1 mg) and a placebo group. The x-axis represents visit time points (baseline, 6, 12, 18, and 24 months) while the y-axis represents percent change. Various lines represent treatment groups with changes trend data indicated throughout the study period.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 07)

Label for estradiol transdermal system, USP, providing continuous once-weekly delivery. The label specifies transdermal use only and contains one transdermal system per package. It includes the Zydus Pharmaceuticals USA Inc. logo and notes the product is Rx only. Some details regarding specific strength and inactive ingredients are partially obscured.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 08)

Illustration showing the Estradiol Transdermal System, USP patch with labeling indicating it is for continuous once-weekly transdermal delivery. The image highlights a top tear notch for opening and demonstrates how to peel back the patch package for use. The label includes manufacturer information, Zydus Pharmaceuticals USA Inc., and indicates Rx only.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 09)

Illustrations showing the estradiol transdermal patch with its protective film and backing. One figure depicts the patch in its packaging with the protective film being peeled off; the other shows hands peeling the protective backing from the estradiol patch, demonstrating how to prepare it for application.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 10)

An instructional illustration showing the application sites for a transdermal patch of estradiol. Figure E shows the patch being applied to the lower abdomen area. Figure F shows the patch being applied to the buttocks.*

FDA Label Image

Estradiol Transdermal System (456a0f03 C5af 42fd A057 A706354179c4 11)

An instructional line drawing labeled Figure G showing a hand applying a rectangular patch to the skin, illustrating the placement of a transdermal patch on the body.*

FDA Label Image

Estradiol Transdermal System, 0.025 mg/day (456a0f03 C5af 42fd A057 A706354179c4 12)

Packaging label for estradiol transdermal system USP 0.025 mg/day patch by Zydus Pharmaceuticals USA Inc. The label includes dosage strength, application instructions for weekly use, barcode, and manufacturer details. It specifies continuous delivery once-weekly, transdermal route, contains 4 transdermal systems, and indicates Rx only status.*

FDA Label Image

Estradiol Transdermal System, 0.0375 mg/day (456a0f03 C5af 42fd A057 A706354179c4 13)

The packaging label for Estradiol Transdermal System, USP, 0.0375 mg/day, by Zydus Pharmaceuticals USA Inc. The label indicates a transdermal patch dosage form for weekly use, containing 2.832 mg estradiol to deliver 0.0375 mg daily. The label highlights storage instructions, safety warnings, and manufacturing by Zydus Lifesciences Ltd., Ahmedabad, India.*

FDA Label Image

Estradiol Transdermal System, 0.05 mg/day (456a0f03 C5af 42fd A057 A706354179c4 14)

Estradiol Transdermal System, USP 0.05 mg/day patch packaging label showing the name, strength, and dosage form. The label includes instructions for weekly application, storage conditions, and notes that it contains 4 patches. Manufactured by Zydus Lifesciences Ltd. and distributed by Zydus Pharmaceuticals USA Inc. The label features barcodes, NDC 68382-326-04, and prominent branding.*

FDA Label Image

Estradiol Transdermal System, 0.06 mg/day (456a0f03 C5af 42fd A057 A706354179c4 15)

Estradiol Transdermal System, USP 0.06 mg/day. Prescription patch for transdermal use, packaged in a carton displaying dosage strength prominently. Label includes directions for weekly application, inactive ingredients, storage instructions, and manufacturer details as Zydus Lifesciences Ltd. with distribution by Zydus Pharmaceuticals USA Inc. The package contains 4 transdermal systems and bears NDC 68382-327-04.*

FDA Label Image

Estradiol Transdermal System, 0.075 mg/day (456a0f03 C5af 42fd A057 A706354179c4 16)

Carton label for estradiol transdermal system, USP 0.075 mg/day patch. The label includes text indicating it provides continuous delivery once weekly, for transdermal use only, and contains 4 transdermal systems. It shows NDC 68382-328-04 and the labeler Zydus Pharmaceuticals USA Inc., with the manufacturer listed as Zydus Lifesciences Ltd., Ahmedabad, India. The label also contains usage instructions and a barcode.*

FDA Label Image

Estradiol Transdermal System, 0.1 mg/day (456a0f03 C5af 42fd A057 A706354179c4 17)

Packaging label for estradiol transdermal system, USP patch delivering 0.1 mg/day. The label includes dosage form, strength, NDC number 68382-329-04, manufacturer Zydus Lifesciences Ltd., and distributor Zydus Pharmaceuticals (USA) Inc. Instructions note weekly application and storage conditions. The label indicates a package contains 4 transdermal systems and is Rx only.*

* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.