Timolol Maleate Solution/ Drops
Pricing Report NDC 68682-045-50

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The latest wholesale acquisition cost for Timolol Maleate (NDC 68682-045-50) is $17.72158 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Sep 17, 2025.

As a a human prescription drug provided by Oceanside Pharmaceuticals, this medication is distributed in a 1 BOTTLE, DROPPER in 1 CARTON / 5 mL in 1 BOTTLE, DROPPER configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$17.72158
Per ML

Effective Date
Sep 17, 2025
Data Status
As of Oct 01, 2025
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 BOTTLE, DROPPER in 1 CARTON / 5 mL in 1 BOTTLE, DROPPER
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Oct 2018, the NADAC wholesale price for (NDC ) has moved within a range of $11.17747 to $45.17371 per ML. Over this 6 years and 11 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$20.3373 - $45.1737
Market Volatility
122.12% Variance
Latest Trend
8.64%
Date Unit Price Unit Source Method Rate
Sep 17, 2025 $20.97704 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 17, 2025 $17.72158 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 20, 2025 $22.96079 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 20, 2025 $18.06114 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $23.60333 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $18.28680 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $24.17693 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $18.50764 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $24.50380 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $18.67365 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $24.67520 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $19.55856 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $24.42960 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $20.41119 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $24.80567 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $21.08403 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $25.14827 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $21.24877 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $25.93427 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2024 $25.60940 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $26.11000 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $24.89371 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $24.76680 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $24.76680 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Aug 21, 2024 $26.03720 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 21, 2024 $19.95610 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $26.03720 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $16.35140 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 19, 2024 $22.11480 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 19, 2024 $14.96090 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 22, 2024 $21.20420 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 22, 2024 $11.17747 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $22.05220 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $19.69050 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 20, 2024 $26.91440 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 17, 2024 $23.40900 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 17, 2024 $23.40900 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Dec 20, 2023 $23.51667 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 22, 2023 $27.13525 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 18, 2023 $26.37840 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 18, 2023 $26.37840 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Oct 18, 2023 $31.17033 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 20, 2023 $29.30889 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 23, 2023 $23.49440 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 23, 2023 $23.49440 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jul 19, 2023 $27.97967 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 19, 2023 $27.97967 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jun 21, 2023 $23.87667 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 17, 2023 $20.33733 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 22, 2023 $33.87650 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 22, 2023 $33.87650 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Feb 22, 2023 $25.66733 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 22, 2023 $25.66733 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jan 18, 2023 $28.00000 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 18, 2023 $31.29100 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 18, 2023 $31.29100 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Dec 21, 2022 $26.41933 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 23, 2022 $26.44067 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 21, 2022 $24.79560 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 21, 2022 $24.79560 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jan 19, 2022 $31.31640 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 19, 2022 $31.31640 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Sep 22, 2021 $37.32880 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 22, 2021 $37.32880 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Sep 22, 2021 $33.55760 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 22, 2021 $33.55760 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jun 23, 2021 $30.59433 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 23, 2021 $30.59433 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Mar 17, 2021 $38.16114 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 17, 2021 $38.16114 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jan 20, 2021 $36.16971 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 20, 2021 $36.16971 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Dec 23, 2020 $44.58000 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 21, 2020 $40.23350 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 21, 2020 $40.23350 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Oct 21, 2020 $42.07300 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 21, 2020 $42.07300 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Sep 23, 2020 $27.35280 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 23, 2020 $35.20289 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 22, 2020 $45.16160 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 22, 2020 $45.16160 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jun 17, 2020 $42.05067 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 20, 2020 $43.52320 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2020 $45.17371 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2020 $43.07520 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2020 $43.07520 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Feb 19, 2020 $39.13125 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2020 $39.13125 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Dec 18, 2019 $44.90900 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2019 $44.90900 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Oct 23, 2019 $37.14356 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2019 $37.14356 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Oct 23, 2019 $39.46400 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2019 $39.46400 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Sep 18, 2019 $31.22960 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2019 $30.86720 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2019 $30.86720 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Oct 17, 2018 $40.02360 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 17, 2018 $40.02360 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026