Pyridostigmine Bromide Solution
Pricing Report NDC 68682-307-05

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The latest wholesale acquisition cost for Pyridostigmine Bromide (NDC 68682-307-05) is $0.84210 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jul 23, 2025.

As a a human prescription drug provided by Oceanside Pharmaceuticals, this medication is distributed in a 473 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.84210
Per ML

Effective Date
Jul 23, 2025
Billable Units
473 ML
Estimated Package Price
$398.31
Data Status
As of Jul 30, 2025
C/I - Chain or Independent Pharmacy
Package NDC
Description
473 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2024, the NADAC wholesale price for (NDC ) has moved within a range of $0.83763 to $1.40699 per ML. Over this 1 year and 3 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.8376 - $1.4070
Market Volatility
67.97% Variance
Latest Trend
1.71%
Date Unit Price Unit Source Method Rate
Jul 23, 2025 $0.84210 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $0.85675 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $0.86051 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $0.83763 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $0.87215 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $0.95846 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $1.00607 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $0.96716 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2024 $0.99474 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $0.85885 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $0.87972 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 21, 2024 $0.88441 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $0.85689 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 19, 2024 $0.88482 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 22, 2024 $0.90857 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $1.40699 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026