Dihydroergotamine Mesylate Spray
Pricing Report NDC 68682-357-10

Latest NADAC: $32.76948 per ML · Effective Sep 17, 2025 · Est. package price $262.16 (8 ML)
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The latest wholesale acquisition cost for Dihydroergotamine Mesylate (NDC 68682-357-10) is $32.76948 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Sep 17, 2025.

As a a human prescription drug provided by Oceanside Pharmaceuticals, this medication is distributed in a 8 VIAL in 1 KIT / 1 mL in 1 VIAL configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$32.76948
Per ML

Pricing Unit
Per ML Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Sep 17, 2025
Billable Units
8 ML
Estimated Package Price
$262.16
Data Status
As of Oct 01, 2025
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
68682-357-10
Description
8 VIAL in 1 KIT / 1 mL in 1 VIAL
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Dec 2013, the NADAC wholesale price for (NDC ) has moved within a range of $32.45369 to $413.98800 per ML. Over this 11 years and 8 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$32.4537 - $413.9880
Market Volatility
1,175.63% Variance
Latest Trend
0.47%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Sep 17, 2025 $32.76948 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 20, 2025 $32.61733 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $32.62185 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $33.56062 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $35.55546 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $37.01427 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $37.03048 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $36.18848 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $35.70937 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $35.12975 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2024 $34.83206 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $34.95232 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: October 07, 2026