Combipatch (estradiol/norethindrone Acetate Transdermal System) Patch, Extended Release
Pricing Report NDC 68968-0525-8
Current NADAC: $31.78620 per EA · Effective Sep 23, 2026 · Est. package price $254.29 (8 EA)
Current Package Pricing Information
The current wholesale acquisition cost for Combipatch (estradiol/norethindrone Acetate Transdermal System) (NDC 68968-0525-8) is $31.78620 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Sep 23, 2026.
As a a human prescription drug provided by Noven Therapeutics, Llc, this medication is distributed in a 8 POUCH in 1 CARTON / 1 PATCH in 1 POUCH / 3.5 d in 1 PATCH configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.
NADAC Pricing Summary
NADAC pricing snapshot for this package NDC
Acquisition Cost $31.78620 Per EA
Pricing Unit
Effective Date
Sep 23, 2026
Billable Units
8 EA
Estimated Package Price
$254.29
Data Status
As of Oct 07, 2026
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
Historical Pricing Trends & Acquisition Cost Benchmarks
Since Dec 2014, the NADAC wholesale price for (NDC ) has moved within a range of $10.72170 to $31.83967 per EA. Over this 11 years and 9 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.
Price Range
$10.7217 - $31.8397
$10.7217 - $31.8397
Market Volatility
196.96% Variance
196.96% Variance
Latest Trend
0.02%
0.02%
Recent NADAC Price History
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Sep 23, 2026 | $31.78620 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Aug 19, 2026 | $31.79246 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jul 22, 2026 | $31.81172 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jun 17, 2026 | $31.81898 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| May 20, 2026 | $31.83967 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jan 01, 2026 | $31.83817 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2026 | $31.83817 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 01, 2026 | $31.83817 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Dec 17, 2025 | $31.15281 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Nov 19, 2025 | $31.15265 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Oct 22, 2025 | $31.15886 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Sep 17, 2025 | $31.15963 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
Earlier NADAC Price History
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Aug 20, 2025 | $31.17667 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jul 23, 2025 | $31.16743 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jun 18, 2025 | $31.15898 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| May 21, 2025 | $31.18248 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jan 01, 2025 | $31.22607 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2025 | $31.22607 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 01, 2025 | $31.22607 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Nov 20, 2024 | $29.73997 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Nov 20, 2024 | $29.73997 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Oct 23, 2024 | $29.75027 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Sep 18, 2024 | $29.75027 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Aug 21, 2024 | $29.76966 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jul 17, 2024 | $29.78434 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jun 19, 2024 | $29.73737 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| May 22, 2024 | $29.76306 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jan 01, 2024 | $29.64818 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2024 | $29.64818 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 01, 2024 | $29.64818 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Oct 18, 2023 | $28.50869 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Oct 18, 2023 | $28.50869 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2023 | $28.49344 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2023 | $28.49344 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 01, 2023 | $28.49344 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Jan 01, 2022 | $27.66407 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2022 | $27.66407 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 01, 2022 | $27.66407 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Oct 20, 2021 | $26.34723 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Oct 20, 2021 | $26.34723 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2021 | $26.42411 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2021 | $26.42411 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 01, 2021 | $26.42411 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Oct 21, 2020 | $24.85875 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Oct 21, 2020 | $24.85875 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2020 | $24.85463 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2020 | $24.85463 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 01, 2020 | $24.85463 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Oct 23, 2019 | $22.96125 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Oct 23, 2019 | $22.96125 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2019 | $22.89629 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 01, 2019 | $22.89629 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 01, 2019 | $22.89629 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Oct 17, 2018 | $20.83375 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Oct 17, 2018 | $20.83375 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 04, 2018 | $20.81820 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 04, 2018 | $20.81820 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 04, 2018 | $20.81820 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Nov 22, 2017 | $18.94234 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Nov 22, 2017 | $18.94234 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Feb 22, 2017 | $19.00769 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Feb 22, 2017 | $19.00769 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Feb 22, 2017 | $19.00769 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Jan 04, 2017 | $19.17360 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 04, 2017 | $19.17360 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Sep 21, 2016 | $17.59029 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Sep 21, 2016 | $17.59029 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jul 20, 2016 | $17.23354 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Jul 20, 2016 | $17.23354 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Jan 05, 2016 | $17.64474 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 05, 2016 | $17.64474 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Aug 19, 2015 | $16.05527 | EA | C/I - Chain or Independent Pharmacy | Code 1 | B - Brand |
| Aug 19, 2015 | $16.05527 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jun 05, 2015 | $16.05822 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jun 05, 2015 | $16.05822 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 05, 2015 | $13.39301 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Jan 05, 2015 | $13.39301 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
| Jan 05, 2015 | $13.39301 | EA | C/I - Chain or Independent Pharmacy | Code 4 | B - Brand |
| Dec 03, 2014 | $10.72170 | EA | C/I - Chain or Independent Pharmacy | Code 2 | B - Brand |
| Dec 03, 2014 | $10.72170 | EA | C/I - Chain or Independent Pharmacy | Code 3 | B - Brand |
Pricing Methodology Legend
- Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
- Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
- Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
- Code 4: The NADAC was carried forward from the previous file.
Understanding NADAC Pricing Data
The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.
Important Price Distinction:
The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.
NADAC Pricing Data Last Updated on: October 07, 2026
