Product Images Adapalene And Benzoyl Peroxide Swab

This text is the result of a data analysis study comparing the efficacy of Adapalene and Benzoyl Peroxide on inflammatory and non-inflammatory skin lesions. The study was conducted on 142 people who received Adapalene and 143 people who received Benzoyl Peroxide. The study showed that Adapalene was more effective in improving skin lesions with a higher percentage of reduction in mean absolute change for inflammatory and non-inflammatory lesions. However, the text also mentions a "mean percent increase of 13.2%" which is unclear without more context.*

Table 1 reports the drug-related adverse events during clinical trials of Adapalene and Benzoyl Peroxide Vehicle for 12 weeks. The table shows that out of 564 subjects treated with Adapalene, 14% reported adverse events including dry skin, contact dermatitis, application site burning and skin irritation, among others. On the other hand, out of 489 subjects treated with Benzoyl Peroxide Vehicle, only 4% reported adverse events including dry skin, application site irritation, and others. Table 2 presents the local tolerability evaluations conducted during the clinical trials.*

The text provides a table that shows the incidence and severity of local cutaneous irritation observed during controlled clinical trials, where different treatment emergent signs and symptoms such as erythema, scaling, dryness, and stinging/burning were evaluated for 12 weeks. The maximum severity occurred during the first week of treatment and decreased thereafter.*

The table shows the clinical efficacy of Adapalene and Benzoyl Peroxide Gel at Week 12 based on various parameters such as IGA, inflammatory lesions, and non-inflammatory lesions. The percentage change in parameters is also mentioned. The study conducted for Adapalene 0.1% in Vehicle gel is divided into two parts (Study 1 and Study 2), whereas the efficacy of Benzoyl Peroxide 2.5% and 25% in Vehicle gel is shown separately.*