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WELCOME TO THE OBAGI - C RX SYSTEM OF SKIN CARE PRODUCTS!For external use onlyRx only
Patient Medication Information
For topical use onlyHelp correct early signs of aging and skin damage before they become a problem! This earlyintervention system helps keep your skin protected and proactively addresses emerging signs ofskin dmaage to refresh and maintain youthful, healthy - looking skin. The Obagi - C Rx System is a unique skin care regumen that combines the benefits of both prescription - strengthhydroquinone and the power of Vitamin - C.Please read this product infomration prior to use of the Obagi - C Rx System. Any questionsregarding your particular skin care regimen should be directed to your physician. Moreinformation about the Obagi - C Rx System or other Obagi systems is available at our website atwww.obagi.com.
Information For Patients
Each gram of Obagi - C Rx System C - Clarifying Serum for Normal to Dry Skin contains:Active ingredient:Hydroquinone USP, 4 % (40 mg / g)Inactive Ingredients:propylene glycol, water, ascorbic acid, propylene carbonate, sodium lauryl sulfateEach gram of Obagi - C Rx System C - Clarifying Serum for Normal to Oily Skin contains:Active Ingredient:Hydroquinone USP, 4 % (40 mg / g)Inactive ingredients:water, propylene glycol, alcohol denat., dipropylene glycol, ascorbic acid, propylene carbonate,sodium lauryl sulfate, fragranceEach gram of Obagi - C Rx System C - Therapy Night Cream contains:Active ingredient:Hydroquinone USP, 4 % (40 mg / g)Inactive Ingredients:water, glycerin, cetyl alcohol, PPG - 2 myristyl ether propionate, sodium lauryl sulfate, TEA - salicylate, lactic acid, phenyl trimethicone, tocopheryl acetate, sodium metabisulfite, ascorbicacid, methylparaben, disodium EDTA, propylparaben, saponins, BHT
Hydroquinone is 1,4 - bensenediol. Hydroquinone occurs as fine, white needles. The drug is freelysoluble in water and in alcohol. Chemically, hydroquinone is designated as p - dihydroxybenzene;the empirical formula is C6H6O2; molecular weight is 110.11 g / moL.
Topical application of hydroquinone produces a reversible depigmentation of the skin byinhibition of the enzymatic oxidation of 3, 4 - dihydroxyphenylalanine (DOPA) andsuppression of other melanocyte metabolic processes. Exposure to sunlight or ultraviolet lightwill cause repigmentation of the bleached areas, which may be prevented by the use ofsunblocking agents or sunscreen agents contained in the Obagi - C Rx System sun Shield MatteBroad Spectrum SPF 50.
Indications & Usage
The gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation.
Dosage & Administration
A thin application should be applied once or twice daily or as directed by a physician. noimprovement is seen after three (3) months of treatment, use of this product should bediscontinued. Sun exposure may be limited by using a sunscreen agent, a sunblocking agent,or protective clothing to cover bleached skin when using and after using this product in order toprevent darkening from reoccuring.
Hydroquinoone is a skin - bleaching agent, which may produce unwanted cosmetic effects if notused as directed. The physician should be familiar with the contents of this insert before prescribing or dispensing this product.Test for skin sensitivity before using by applying a small amount to an unbroken patch of skinand check within 24 hours. Minor redness is not a contraindication, but where there is itchingor vesicle formation or excessive inflammatory response, product should be discontinued and physician consulted. Close patient supervision is recommended.Avoid contact with eyes, nose, mouth, and lips. In case of accidental contact, patient shouldrinse thoroughly with water and contact a physician.Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.The Obagi - C Rx Therapy Night Cream contains sodium metabisulfite, a sulfite thatmay cause allergic - type reactions including anaphylactic symptoms and life - threatening orless severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfitesensitivity in the general populationis unknown and probably low. Sulfite sensitivity is seenmore frequently in asthmatic than in nonasthmatic people.
(also see WARNINGS)Treatment should be limited to relatively small areas of the body at one time since somepatients experience a transient skin reddening and a mild burning sensation, which does notpreclude treatment.Pregnancy Category CAnimal reproduction studies have not been conducted with topical hydroquinone. It is alsonot known whether hydroquinone can case fetal harm when used topically on a pregnant womanor affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone isabsorbed systemically. Topical hydroquinone should be used on pregnant women only whenclearly indicated.Nursing MothersIt is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution isadvised when topical hydroquinone is used by a nursing mother.Pediatric UsageSafety and effectiveness in children below the age of 12 years have not been established.
No systemic adverse reactions have been reported. Occasional hypersensitivity (localizedcontact dermatitis) may occur, in which case the product should be discontinued and physiciannotified immediately.
People with prior history of sensitivity or allergic reaction to this product or any of itsingredients should not use it. The safety of topical hydroquinone use during pregnancyor in children (12 years and under) has not been established.
Storage And Handling
Store at controlled room temperature 15 C - 25 C (59 F - 77 F). Keep out of direct sunlight
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