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Amerfresh's fluoride toothpaste is designed to prevent dental cavities with its active ingredient of 0.22% sodium fluoride. It is important to keep the product out of the reach of children under 6 years old and to seek medical attention if accidentally swallowed. Parents are encouraged to teach children under 12 to properly brush and rinse their teeth. Brushing is recommended after meals and at least twice a day for adults and children 6 years and older, or as directed by a dentist or doctor. The toothpaste, weighing 0.850z (24g), is manufactured in China and distributed by AMERCARE Products Inc. in Woodille, WA. The product includes inactive ingredients such as calcium carbonate, sorbitol, and flavor. The product should be used with adult supervision for children until they are able to use it unsupervised. The batch number and manufacture date are listed on the crimp, with an expiration date indicated as being three years from the manufacturing date.*