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This text appears to be a combination of numerical and textual elements that may have originated from a scientific study or clinical trial. It includes dosages for a hormone therapy or treatment called Estradiol, a placebo, and information indicating a statistically significant difference between the two treatments. However, without additional context or proper formatting, it is difficult to provide a more detailed or accurate summary.*

The text shows percentage change from baseline during a treatment period of Estradiol at different dosages (0.025mg/day and 0.0375mg/day) and placebo. The results were obtained at weeks 2, 7, and 104. There is also reference to the state of Lok Lo s oo and Estadol01 mgydy, but it is not clear how this information relates to the rest of the content.*

The text is a product name and instructions for a transdermal system. The system needs to be changed only on specific days of the week (Sun/Wed, Mon/Thu, Tue/Fri, Wed/Sat, Thu/Sun, Fri/Mon, Sat/Tue).*

Each DOTTI® transdermal system contains 0.940 mg of estradiol, USP and delivers 0.075 mg/day. It should be kept out of reach of children and is for transdermal use only. The patch should be stored at 20° to 25°C (68° to 77°F), with excursions permitted between 15° to 30°C (59° to 86°F). The patch should be applied immediately after removal from the pouch and not stored unpouched. The package is not child-resistant. The product is available in a package containing 8 systems and can only be obtained with a prescription.*