Naloxone Hydrochloride Injection
Pricing Report NDC 76329-3369-1

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Naloxone Hydrochloride (NDC 76329-3369-1) is $13.69291 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by International Medication Systems, Limited, this medication is distributed in a 10 SYRINGE in 1 BOX / 2 mL in 1 SYRINGE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$13.69291
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
10 SYRINGE in 1 BOX / 2 mL in 1 SYRINGE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jul 2016, the NADAC wholesale price for (NDC ) has moved within a range of $10.31681 to $17.37813 per ML. Over this 9 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$10.3168 - $17.3781
Market Volatility
68.44% Variance
Latest Trend
1.96%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $13.69291 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $13.43007 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $13.03692 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $12.86187 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $11.89929 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $11.67991 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $11.30008 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $11.63043 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $11.41497 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $11.29394 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $11.82598 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $12.29693 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $12.76993 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $12.65820 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $12.49800 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $12.15732 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $11.71002 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $11.50758 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $11.39371 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $11.80988 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $11.22495 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $11.13815 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $11.13815 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $11.63020 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $10.76247 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $10.47233 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $10.31681 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 19, 2018 $15.49120 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 19, 2018 $15.49120 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jun 20, 2018 $15.69708 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 20, 2018 $15.69708 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 17, 2018 $15.47910 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2018 $15.47910 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Dec 21, 2016 $15.24320 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2016 $15.24320 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 17, 2016 $15.98030 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2016 $15.98030 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 20, 2016 $17.37813 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026