Isosorbide Mononitrate Tablet
Pricing Report NDC 81665-103-10

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Isosorbide Mononitrate (NDC 81665-103-10) is $3.39010 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Omnivium Pharmaceuticals Llc., this medication is distributed in a 100 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$3.39010
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$339.01
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Feb 2025, the NADAC wholesale price for (NDC ) has moved within a range of $0.18839 to $3.39022 per EA. Over this 1 year and 4 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.1884 - $3.3902
Market Volatility
1,699.58% Variance
Latest Trend
0.18%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $3.39010 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 20, 2026 $3.38415 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 22, 2026 $3.37618 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 18, 2026 $3.37618 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 18, 2026 $3.38506 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 21, 2026 $3.39022 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 17, 2025 $3.38568 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 19, 2025 $3.37711 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 22, 2025 $3.37379 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 17, 2025 $3.37503 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 20, 2025 $3.36835 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 23, 2025 $3.36076 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 18, 2025 $3.35316 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 21, 2025 $3.35316 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 19, 2025 $0.19212 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 19, 2025 $0.19212 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
Feb 05, 2025 $0.18839 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026