Amoxicillin And Clavulanate Potassium Tablet, Coated
Pricing Report NDC 81964-221-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Amoxicillin And Clavulanate Potassium (NDC 81964-221-01) is $0.27470 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Usantibiotics, Llc, this medication is distributed in a 100 TABLET, COATED in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.27470
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$27.47
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET, COATED in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Mar 2023, the NADAC wholesale price for (NDC ) has moved within a range of $0.26312 to $0.37197 per EA. Over this 3 years and 3 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.2631 - $0.3720
Market Volatility
41.37% Variance
Latest Trend
2.55%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.27470 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 17, 2026 $0.27470 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 20, 2026 $0.28188 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 20, 2026 $0.28188 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 22, 2026 $0.28438 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 22, 2026 $0.28438 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 18, 2026 $0.28117 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 18, 2026 $0.28117 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 18, 2026 $0.27114 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 18, 2026 $0.27114 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 21, 2026 $0.27974 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 21, 2026 $0.27974 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 17, 2025 $0.29770 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 17, 2025 $0.29770 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 19, 2025 $0.30802 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 19, 2025 $0.30802 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 22, 2025 $0.29870 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 22, 2025 $0.29870 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 17, 2025 $0.28558 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 17, 2025 $0.28558 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 20, 2025 $0.28175 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 20, 2025 $0.28175 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 23, 2025 $0.29114 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 23, 2025 $0.29114 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 18, 2025 $0.30119 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 18, 2025 $0.30119 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 21, 2025 $0.31937 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 21, 2025 $0.31937 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 23, 2025 $0.32907 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 23, 2025 $0.32907 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 19, 2025 $0.34183 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 19, 2025 $0.34183 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 19, 2025 $0.32240 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 19, 2025 $0.32240 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 22, 2025 $0.29656 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 22, 2025 $0.29656 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 01, 2025 $0.27322 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 18, 2024 $0.27322 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 20, 2024 $0.26312 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 23, 2024 $0.27807 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 18, 2024 $0.28945 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 21, 2024 $0.28836 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 17, 2024 $0.26833 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 19, 2024 $0.31381 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 22, 2024 $0.27040 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 17, 2024 $0.27809 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 20, 2024 $0.34128 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 21, 2024 $0.33968 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 17, 2024 $0.37197 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 20, 2023 $0.35641 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 22, 2023 $0.32659 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 18, 2023 $0.33189 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 20, 2023 $0.29889 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 23, 2023 $0.30859 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 19, 2023 $0.34409 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 21, 2023 $0.35915 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 17, 2023 $0.33593 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 19, 2023 $0.32529 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 22, 2023 $0.32681 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 08, 2023 $0.33644 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026