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The following 6 images provide visual information about the product associated with Ogsiveo NDC 82448-050 by Springworks Therapeutics, Inc., such as packaging, labeling, and the appearance of the drug itself. This resource could be helpful for medical professionals, pharmacists, and patients seeking to verify medication information and ensure they have the correct product.

The structural formula for nirogacestat hydrobromide is: OGSIVEO oral tablets contain nirogacestat (as nirogacestat hydrobromide), a gamma (ɣ) secretase inhibitor. Nirogacestat hydrobromide is chemically known as (S)-2-(((S)-6,8-Difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl) pentanamide dihydrobromide. The empirical formula is C27H43Br2F2N5O and the molecular weight is 651.48 g/mol. Nirogacestat hydrobromide is a white to off white powder with an aqueous solubility of 11.4 mg/mL and a pH of 4.4 in water at 25C. Nirogacestat dihydrobromide is highly soluble at low pH, however the solubility significantly decreases at pH > 6.0. The molecule has pKa’s of 5.77 and 7.13. - nirogacestat 01

The structural formula for nirogacestat hydrobromide is: OGSIVEO oral tablets contain nirogacestat (as nirogacestat hydrobromide), a gamma (ɣ) secretase inhibitor. Nirogacestat hydrobromide is chemically known as (S)-2-(((S)-6,8-Difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl) pentanamide dihydrobromide. The empirical formula is C27H43Br2F2N5O and the molecular weight is 651.48 g/mol. Nirogacestat hydrobromide is a white to off white powder with an aqueous solubility of 11.4 mg/mL and a pH of 4.4 in water at 25C. Nirogacestat dihydrobromide is highly soluble at low pH, however the solubility significantly decreases at pH > 6.0. The molecule has pKa’s of 5.77 and 7.13. - nirogacestat 01

Figure 1 - nirogacestat 02

Figure 1 - nirogacestat 02

PRINCIPAL DISPLAY PANELNDC 82448-050-18Rx OnlyOgsiveo50 mg180 tablets - nirogacestat 03

PRINCIPAL DISPLAY PANELNDC 82448-050-18Rx OnlyOgsiveo50 mg180 tablets - nirogacestat 03

PRINCIPAL DISPLAY PANELNDC 82448-050-18Rx OnlyOgsiveo50 mg180 tablets - nirogacestat 04

PRINCIPAL DISPLAY PANELNDC 82448-050-18Rx OnlyOgsiveo50 mg180 tablets - nirogacestat 04

PRINCIPAL DISPLAY PANELNDC 82448-050-18Rx OnlyOgsiveo50 mg180 tablets - nirogacestat 05

PRINCIPAL DISPLAY PANELNDC 82448-050-18Rx OnlyOgsiveo50 mg180 tablets - nirogacestat 05

PRINCIPAL DISPLAY PANELNDC 82448-050-18Rx OnlyOgsiveo50 mg180 tablets - nirogacestat 06

PRINCIPAL DISPLAY PANELNDC 82448-050-18Rx OnlyOgsiveo50 mg180 tablets - nirogacestat 06