Lactulose Solution
Pricing Report NDC 83745-405-08

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Lactulose (NDC 83745-405-08) is $0.02140 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Apozeal Pharmaceuticals Inc, this medication is distributed in a 237 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.02140
Per ML

Effective Date
Jun 17, 2026
Billable Units
237 ML
Estimated Package Price
$5.07
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
237 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2025, the NADAC wholesale price for (NDC ) has moved within a range of $0.01675 to $0.02541 per ML. Over this 1 year and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0172 - $0.0254
Market Volatility
47.99% Variance
Latest Trend
2.73%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.02140 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $0.02250 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $0.01952 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.02200 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.02365 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.01892 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.02248 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.02388 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.01853 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.02215 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.02454 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.01909 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.02112 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.02432 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.01873 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.01894 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.02438 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.01853 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.01737 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.02448 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.01803 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.01717 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.02469 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.01675 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.01774 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.02487 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.01675 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 24, 2025 $0.01808 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.02488 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.02541 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 13, 2025 $0.01809 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 23, 2025 $0.02539 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.02533 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.02461 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.02462 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 09, 2025 $0.02458 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026