X-treme Cream Propolis Sunscreen Spf 45 Cream
NDC Package 84378-101-74

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

X-treme Cream Propolis Sunscreen Spf 45 (x-treme cream) cream is a human otc drug administered via topical route. This formulation utilizes a cream delivery system. Marketed by Epicuren Discovery, this product is identified by NDC 84378-101 and is authorized under FDA application M020.

Identification & Billing

NDC Package Code
84378-101-74
Package Description
74 g in 1 TUBE
Product Code
84378-101
11-Digit Billing Format
84378010174

Clinical Specifications

Proprietary Name
X-treme Cream Propolis Sunscreen Spf 45
Non-Proprietary Name
X-treme Cream
Substance Name
Homosalate; Octinoxate; Octisalate; Octocrylene; Zinc Oxide
Dosage Form
Cream - An emulsion, semisolid3 dosage form, usually containing > 20% water and volatiles5 and/or < 50% hydrocarbons, waxes, or polyols as the vehicle. This dosage form is generally for external application to the skin or mucous membranes.
Administration Route
Topical - Administration to a particular spot on the outer surface of the body. The E2B term TRANSMAMMARY is a subset of the term TOPICAL.
Active Ingredient(s)

Regulatory & Marketing

Labeler Name
Epicuren Discovery
Product Type
Human Otc Drug
FDA Application #
M020
Marketing Category
OTC MONOGRAPH DRUG -
Start Marketing Date
07-30-2025
Listing Expiration
12-31-2026
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 84378-101-74 identifies a specific commercial package of 74 g in 1 tube of X-treme Cream Propolis Sunscreen Spf 45, a human over the counter drug labeled by Epicuren Discovery. This cream is formulated for topical use and contains homosalate; octinoxate; octisalate; octocrylene; zinc oxide as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Epicuren Discovery on July 30, 2025. The current certification is valid through December 31, 2026.

How is this Epicuren Discovery product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 84378010174. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
84378-101-74
11-Digit CMS (5-4-2)
84378-0101-74

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.