Enbumyst Spray
NDC Package 84388-005-06
Package Information
Enbumyst (bumetanide) sprays is bumetanide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This formulation utilizes a spray delivery system. Marketed by Corstasis Usa Llc, this product is identified by NDC 84388-005 and is authorized under FDA application NDA219500.
Identification & Billing
- RxCUI: 2724437 - bumetanide 0.5 MG in 0.1 ML Nasal Spray
- RxCUI: 2724437 - bumetanide 5 MG/ML Nasal Spray
- RxCUI: 2724437 - bumetanide 0.5 MG per 0.1 ML Nasal Spray
- RxCUI: 2724443 - Enbumyst 0.5 MG in 0.1 ML Nasal Spray
- RxCUI: 2724443 - bumetanide 5 MG/ML Nasal Spray [Enbumyst]
Clinical Specifications
Regulatory & Marketing
Hierarchy Structure
- 84388 - Corstasis Usa Llc
- 84388-005 - Enbumyst
- 84388-005-06 - 6 BLISTER PACK in 1 CARTON / 1 VIAL, SINGLE-DOSE in 1 BLISTER PACK / .1 mL in 1 VIAL, SINGLE-DOSE
- 84388-005 - Enbumyst
The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.
* Please review the full disclaimer at the bottom of this page.
Other Available Packages
The following commercial packages are registered under the same Product NDC (84388-005). Click a package code to view its specific billing and regulatory data.
* Please review the full disclaimer at the bottom of this page.
Frequently Asked Questions
What is the distribution configuration for this product package?
The code 84388-005-06 identifies a specific commercial package of 6 blister pack in 1 carton / 1 vial, single-dose in 1 blister pack / .1 ml in 1 vial, single-dose of Enbumyst, a human prescription drug labeled by Corstasis Usa Llc. This product is billed for "EA" each discreet unit and contains an estimated amount of 1 billable units per package. This spray is formulated for nasal use and contains bumetanide as the active substance.
Is this product currently listed with the FDA?
Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Corstasis Usa Llc on September 12, 2025. The current certification is valid through December 31, 2027.
What are the primary indications for this medication?
Bumetanide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. Bumetanide is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt.
How is this Corstasis Usa Llc product billed for insurance claims?
For medical billing and reimbursement, this package follows the 11-digit CMS format: 84388000506. Quantities are measured in per "each", products billed on a per each basis are usually products dispensed in discreet units.. There are 1 total billable units per package. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.
11-Digit Code Conversion
Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:
Note: The zero is added to the Product segment to maintain the 5-4-2 structure.
