Evesse Lotion
NDC Package 87143-420-04

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Evesse (hydrocortisone butyrate) lotions is a medication used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). This formulation utilizes a lotion delivery system. Marketed by Perfero Pharma, Inc., this product is identified by NDC 87143-420 and is authorized under FDA application ANDA209556.

Identification & Billing

NDC Package Code
87143-420-04
Package Description
118 mL in 1 BOTTLE
Product Code
87143-420
11-Digit Billing Format
87143042004
RxNorm Crosswalk

Clinical Specifications

Proprietary Name
Evesse
Non-Proprietary Name
Hydrocortisone Butyrate
Substance Name
Hydrocortisone Butyrate
Dosage Form
Lotion - An emulsion, liquid1 dosage form. This dosage form is generally for external application to the skin.2
Administration Route
Topical - Administration to a particular spot on the outer surface of the body. The E2B term TRANSMAMMARY is a subset of the term TOPICAL.
Active Ingredient(s)
HYDROCORTISONE BUTYRATE 1 mg/mL
Pharmacologic Class
Usage Information
This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Hydrocortisone butyrate reduces the swelling, itching, and redness that can occur in these types of conditions. The topical solution is used to treat severe dandruff (seborrheic dermatitis). This medication is a medium-strength corticosteroid.

Regulatory & Marketing

Labeler Name
Perfero Pharma, Inc.
Product Type
Human Prescription Drug
FDA Application #
ANDA209556
Marketing Category
ANDA - A product marketed under an approved Abbreviated New Drug Application.
Start Marketing Date
05-04-2026
Listing Expiration
12-31-2027
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 87143-420-04 identifies a specific commercial package of 118 ml in 1 bottle of Evesse, a human prescription drug labeled by Perfero Pharma, Inc.. This lotion is formulated for topical use and contains hydrocortisone butyrate as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Perfero Pharma, Inc. on May 04, 2026. The current certification is valid through December 31, 2027.

What are the primary indications for this medication?

This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Hydrocortisone butyrate reduces the swelling, itching, and redness that can occur in these types of conditions. The topical solution is used to treat severe dandruff (seborrheic dermatitis). This medication is a medium-strength corticosteroid.

How is this Perfero Pharma, Inc. product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 87143042004. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
87143-420-04
11-Digit CMS (5-4-2)
87143-0420-04

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.