Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA] - N0000191423

Pharmacologic Class Information

Pharmacologic Code N0000191423
Pharmacologic Name Multidrug and Toxin Extrusion Transporter 1 Inhibitors
Pharmacologic Uses
  • cortisol synthesis inhibitor
  • CYP3A inhibitor
  • human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI)
  • kinase inhibitor
  • methyltransferase inhibitor
  • nitroimidazole antimicrobial
Pharmacologic Concept Mechanisms of Action - [MoA]
Pharmacologic Concept Description This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

NDC Products with Multidrug and Toxin Extrusion Transporter 1 Inhibitors

The following table contains 22 products whose active ingredient are classified under the same pharmacologic class Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA].

NDC Proprietary Name Non-Proprietary Name Dosage Form Route Name Company Name Status
0002-2980Retevmo Non-Proprietary Name: SelpercatinibCapsuleOralEli Lilly And CompanyACTIVE
0002-3977Retevmo Non-Proprietary Name: SelpercatinibCapsuleOralEli Lilly And CompanyACTIVE
0024-4512Fexinidazole Non-Proprietary Name: FexinidazoleTabletOralSanofi-aventis U.s. LlcACTIVE
0078-0709Tabrecta Non-Proprietary Name: CapmatinibTablet, Film CoatedOralNovartis Pharmaceuticals CorporationACTIVE
0078-0716Tabrecta Non-Proprietary Name: CapmatinibTablet, Film CoatedOralNovartis Pharmaceuticals CorporationACTIVE
49702-226Tivicay Non-Proprietary Name: Dolutegravir SodiumTablet, Film CoatedOralViiv Healthcare CompanyACTIVE
49702-227Tivicay Non-Proprietary Name: Dolutegravir SodiumTablet, Film CoatedOralViiv Healthcare CompanyACTIVE
49702-228Tivicay Non-Proprietary Name: Dolutegravir SodiumTablet, Film CoatedOralViiv Healthcare CompanyACTIVE
49702-231Triumeq Non-Proprietary Name: Abacavir Sulfate, Dolutegravir Sodium, LamivudineTablet, Film CoatedOralViiv Healthcare CompanyACTIVE
49702-242Juluca Non-Proprietary Name: Dolutegravir Sodium And Rilpivirine HydrochlorideTablet, Film CoatedOralViiv Healthcare CompanyACTIVE
49702-246Dovato Non-Proprietary Name: Dolutegravir Sodium And LamivudineTablet, Film CoatedOralViiv Healthcare CompanyACTIVE
49702-255Tivicay Pd Non-Proprietary Name: Dolutegravir SodiumTablet, For SuspensionOralViiv Healthcare CompanyACTIVE
50881-026Pemazyre Non-Proprietary Name: PemigatinibTabletOralIncyte CorporationACTIVE
50881-027Pemazyre Non-Proprietary Name: PemigatinibTabletOralIncyte CorporationACTIVE
50881-028Pemazyre Non-Proprietary Name: PemigatinibTabletOralIncyte CorporationACTIVE
53808-1130Tivicay Non-Proprietary Name: Dolutegravir SodiumTablet, Film CoatedOralDoh Central PharmacyACTIVE
72064-110Ayvakit Non-Proprietary Name: AvapritinibTablet, Film CoatedOralBlueprint Medicines CorporationACTIVE
72064-120Ayvakit Non-Proprietary Name: AvapritinibTablet, Film CoatedOralBlueprint Medicines CorporationACTIVE
72064-125Ayvakit Non-Proprietary Name: AvapritinibTablet, Film CoatedOralBlueprint Medicines CorporationACTIVE
72064-130Ayvakit Non-Proprietary Name: AvapritinibTablet, Film CoatedOralBlueprint Medicines CorporationACTIVE
72064-150Ayvakit Non-Proprietary Name: AvapritinibTablet, Film CoatedOralBlueprint Medicines CorporationACTIVE
72065-003Recorlev Non-Proprietary Name: LevoketoconazoleTabletOralXeris Pharmaceuticals, Inc.ACTIVE