Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA] - N0000191423

Name: Table of NDC products with multidrug and toxin extrusion transporter 1 inhibitors
Creator: U.S. Food & Drug Administration
License: https://creativecommons.org/licenses/by-nc-sa/4.0/

Pharmacologic Class Information

Pharmacologic Code	N0000191423
Pharmacologic Name	Multidrug and Toxin Extrusion Transporter 1 Inhibitors
Pharmacologic Uses	cortisol synthesis inhibitor CYP3A inhibitor human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) kinase inhibitor methyltransferase inhibitor nitroimidazole antimicrobial survival of motor neuron 2 (SMN2) splicing modifier
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

NDC Products with Multidrug and Toxin Extrusion Transporter 1 Inhibitors

The table contains 32 products whose active ingredient are classified under the same pharmacologic class Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA].

NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
0002-2980	Retevmo	Non-Proprietary Name: Selpercatinib	Capsule	Oral	Eli Lilly And Company	ACTIVE
0002-3977	Retevmo	Non-Proprietary Name: Selpercatinib	Capsule	Oral	Eli Lilly And Company	ACTIVE
0003-3641	Evotaz	Non-Proprietary Name: Atazanavir And Cobicistat	Tablet	Oral	E.r. Squibb & Sons, L.l.c.	ACTIVE
0024-4512	Fexinidazole	Non-Proprietary Name: Fexinidazole	Tablet	Oral	Sanofi-aventis U.s. Llc	ACTIVE
0069-0227	Lorbrena	Non-Proprietary Name: Lorlatinib	Tablet, Film Coated	Oral	Pfizer Laboratories Div Pfizer Inc	ACTIVE
0069-0231	Lorbrena	Non-Proprietary Name: Lorlatinib	Tablet, Film Coated	Oral	Pfizer Laboratories Div Pfizer Inc	ACTIVE
0078-0709	Tabrecta	Non-Proprietary Name: Capmatinib	Tablet, Film Coated	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
0078-0716	Tabrecta	Non-Proprietary Name: Capmatinib	Tablet, Film Coated	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
49702-226	Tivicay	Non-Proprietary Name: Dolutegravir Sodium	Tablet, Film Coated	Oral	Viiv Healthcare Company	ACTIVE
49702-227	Tivicay	Non-Proprietary Name: Dolutegravir Sodium	Tablet, Film Coated	Oral	Viiv Healthcare Company	ACTIVE
49702-228	Tivicay	Non-Proprietary Name: Dolutegravir Sodium	Tablet, Film Coated	Oral	Viiv Healthcare Company	ACTIVE
49702-231	Triumeq	Non-Proprietary Name: Abacavir Sulfate, Dolutegravir Sodium, Lamivudine	Tablet, Film Coated	Oral	Viiv Healthcare Company	ACTIVE
49702-242	Juluca	Non-Proprietary Name: Dolutegravir Sodium And Rilpivirine Hydrochloride	Tablet, Film Coated	Oral	Viiv Healthcare Company	ACTIVE
49702-246	Dovato	Non-Proprietary Name: Dolutegravir Sodium And Lamivudine	Tablet, Film Coated	Oral	Viiv Healthcare Company	ACTIVE
49702-255	Tivicay Pd	Non-Proprietary Name: Dolutegravir Sodium	Tablet, For Suspension	Oral	Viiv Healthcare Company	ACTIVE
50090-1723	Prezcobix	Non-Proprietary Name: Darunavir Ethanolate And Cobicistat	Tablet, Film Coated	Oral	A-s Medication Solutions	ACTIVE
50242-175	Evrysdi	Non-Proprietary Name: Risdiplam	Powder, For Solution	Oral	Genentech Inc.	ACTIVE
50881-026	Pemazyre	Non-Proprietary Name: Pemigatinib	Tablet	Oral	Incyte Corporation	ACTIVE
50881-027	Pemazyre	Non-Proprietary Name: Pemigatinib	Tablet	Oral	Incyte Corporation	ACTIVE
50881-028	Pemazyre	Non-Proprietary Name: Pemigatinib	Tablet	Oral	Incyte Corporation	ACTIVE
53002-1810	Tivicay	Non-Proprietary Name: Dolutegravir Sodium	Tablet, Film Coated	Oral	Rpk Pharmaceuticals, Inc.	ACTIVE
59676-575	Prezcobix	Non-Proprietary Name: Darunavir Ethanolate And Cobicistat	Tablet, Film Coated	Oral	Janssen Products Lp	ACTIVE
59676-800	Symtuza	Non-Proprietary Name: Darunavir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	Tablet, Film Coated	Oral	Janssen Products Lp	ACTIVE
63539-927	Lorbrena	Non-Proprietary Name: Lorlatinib	Tablet, Film Coated	Oral	U.s. Pharmaceuticals	ACTIVE
72064-110	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
72064-120	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
72064-125	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
72064-130	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
72064-150	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
72065-003	Recorlev	Non-Proprietary Name: Levoketoconazole	Tablet	Oral	Xeris Pharmaceuticals, Inc.	ACTIVE
72607-100	Tazverik	Non-Proprietary Name: Tazemetostat	Tablet, Film Coated	Oral	Epizyme, Inc.	ACTIVE
73462-101	Cosela	Non-Proprietary Name: Trilaciclib	Injection, Powder, Lyophilized, For Solution	Intravenous	G1 Therapeutics, Inc.	ACTIVE