Multidrug and Toxin Extrusion Transporter 2 K Inhibitors [MoA] - N0000193932

Pharmacologic Code	N0000193932
Pharmacologic Name	Multidrug and Toxin Extrusion Transporter 2 K Inhibitors
Pharmacologic Uses	kinase inhibitor methyltransferase inhibitor nitroimidazole antimicrobial survival of motor neuron 2 (SMN2) splicing modifier
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 11 products whose active ingredient are classified under the same pharmacologic class Multidrug and Toxin Extrusion Transporter 2 K Inhibitors [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0024-4512	Fexinidazole	Non-Proprietary Name: Fexinidazole	Tablet	Oral	Sanofi-aventis U.s. Llc	ACTIVE
	0078-0709	Tabrecta	Non-Proprietary Name: Capmatinib	Tablet, Film Coated	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-0716	Tabrecta	Non-Proprietary Name: Capmatinib	Tablet, Film Coated	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	50242-175	Evrysdi	Non-Proprietary Name: Risdiplam	Powder, For Solution	Oral	Genentech Inc.	ACTIVE
	72064-110	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
	72064-120	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
	72064-125	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
	72064-130	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
	72064-150	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
	72607-100	Tazverik	Non-Proprietary Name: Tazemetostat	Tablet, Film Coated	Oral	Epizyme, Inc.	ACTIVE
	73462-101	Cosela	Non-Proprietary Name: Trilaciclib	Injection, Powder, Lyophilized, For Solution	Intravenous	G1 Therapeutics, Inc.	ACTIVE