1 daytime (acetaminophen 650 mg / dextromethorphan HBr 20 mg / guaiFENesin 400 mg / phenylephrine HCl 10 mg in 20 mL Oral Solution) / 1 nighttime (acetaminophen 650 mg / diphenhydrAMINE HCl 25 mg / phenylephrine HCl 10 mg in 20 mL Oral Solution) Pack
RxNorm 1424850

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 1424850 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: 1 daytime (acetaminophen 650 mg / dextromethorphan HBr 20 mg / guaiFENesin 400 mg / phenylephrine HCl 10 mg in 20 mL Oral Solution) / 1 nighttime (acetaminophen 650 mg / diphenhydrAMINE HCl 25 mg / phenylephrine HCl 10 mg in 20 mL Oral Solution) Pack.

The following semantic concepts and normalized strings are associated with this clinical entity:

PSN
1 daytime (acetaminophen 650 mg / dextromethorphan HBr 20 mg / guaiFENesin 400 mg / phenylephrine HCl 10 mg in 20 mL Oral Solution) / 1 nighttime (acetaminophen 650 mg / diphenhydrAMINE HCl 25 mg / phenylephrine HCl 10 mg in 20 mL Oral Solution) Pack
AUI:12810386
SY
1 daytime (acetaminophen 650 mg / dextromethorphan HBr 20 mg / guaifenesin 400 mg / phenylephrine HCl 10 mg per 20 mL Oral Solution) / 1 nighttime (acetaminophen 650 mg / diphenhydramine HCl 25 mg / phenylephrine HCl 10 mg per 20 mL Oral Solution) Pack
AUI:12810387
TMSY
1 daytime (acetaminophen 650 mg / dextromethorphan HBr 20 mg / guaiFENesin 400 mg / phenylephrine HCl 10 mg per 20 mL Oral Solution) / 1 nighttime (acetaminophen 650 mg / diphenhydrAMINE HCl 25 mg / phenylephrine HCl 10 mg per 20 mL Oral Solution) Pack
AUI:12810816
GPCK
{1 (acetaminophen 32.5 mg/ML / dextromethorphan hydrobromide 1 mg/ML / guaifenesin 20 mg/ML / phenylephrine hydrochloride 0.5 mg/ML Oral Solution) / 1 (acetaminophen 32.5 mg/ML / diphenhydramine hydrochloride 1.25 mg/ML / phenylephrine hydrochloride 0.5 mg/ML Oral Solution) } Pack
AUI:12813963
TMSY
{1 (acetaminophen 32.5 mg/ML / dextromethorphan hydrobromide 1 mg/ML / guaiFENesin 20 mg/ML / phenylephrine hydrochloride 0.5 mg/ML Oral Solution) / 1 (acetaminophen 32.5 mg/ML / diphenhydrAMINE hydrochloride 1.25 mg/ML / phenylephrine hydrochloride 0.5 mg/ML Oral Solution) } Pack
AUI:12815527

This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

PSNPrescribable

Prescribable Name (PSN):
1 daytime (acetaminophen 650 mg / dextromethorphan HBr 20 mg / guaiFENesin 400 mg / phenylephrine HCl 10 mg in 20 mL Oral Solution) / 1 nighttime (acetaminophen 650 mg / diphenhydrAMINE HCl 25 mg / phenylephrine HCl 10 mg in 20 mL Oral Solution) Pack
(Atom ID: 12810386)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / guaiFENesin 400 MG / phenylephrine HCl 10 MG in 20 mL Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG in 20 mL Oral Solution) Pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1424850
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12810386
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
PSN
Prescribable Name (Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.)
Source Code
1424850
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

SYPrescribable

Synonym (SY):
1 daytime (acetaminophen 650 mg / dextromethorphan HBr 20 mg / guaifenesin 400 mg / phenylephrine HCl 10 mg per 20 mL Oral Solution) / 1 nighttime (acetaminophen 650 mg / diphenhydramine HCl 25 mg / phenylephrine HCl 10 mg per 20 mL Oral Solution) Pack
(Atom ID: 12810387)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / guaifenesin 400 MG / phenylephrine HCl 10 MG per 20 ML Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydramine HCl 25 MG / phenylephrine HCl 10 MG per 20 ML Oral Solution) Pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1424850
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12810387
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
1424850
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

TMSYPrescribable

Tall Man Lettering Synonym (TMSY):
1 daytime (acetaminophen 650 mg / dextromethorphan HBr 20 mg / guaiFENesin 400 mg / phenylephrine HCl 10 mg per 20 mL Oral Solution) / 1 nighttime (acetaminophen 650 mg / diphenhydrAMINE HCl 25 mg / phenylephrine HCl 10 mg per 20 mL Oral Solution) Pack
(Atom ID: 12810816)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / guaiFENesin 400 MG / phenylephrine HCl 10 MG per 20 ML Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG per 20 ML Oral Solution) Pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1424850
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12810816
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
1424850
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

GPCKPrescribable

Generic Pack (GPCK):
{1 (acetaminophen 32.5 mg/ML / dextromethorphan hydrobromide 1 mg/ML / guaifenesin 20 mg/ML / phenylephrine hydrochloride 0.5 mg/ML Oral Solution) / 1 (acetaminophen 32.5 mg/ML / diphenhydramine hydrochloride 1.25 mg/ML / phenylephrine hydrochloride 0.5 mg/ML Oral Solution) } Pack
(Atom ID: 12813963)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
{1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1424850
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12813963
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
GPCK
Generic Pack ({# (Ingredient + Strength + Dose Form) / # (Ingredient + Strength + Dose Form)} Pack)
Source Code
1424850
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN HUMAN DRUG
US
Drug available for use in Humans

TMSYPrescribable

Tall Man Lettering Synonym (TMSY):
{1 (acetaminophen 32.5 mg/ML / dextromethorphan hydrobromide 1 mg/ML / guaiFENesin 20 mg/ML / phenylephrine hydrochloride 0.5 mg/ML Oral Solution) / 1 (acetaminophen 32.5 mg/ML / diphenhydrAMINE hydrochloride 1.25 mg/ML / phenylephrine hydrochloride 0.5 mg/ML Oral Solution) } Pack
(Atom ID: 12815527)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
{1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / guaiFENesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (acetaminophen 32.5 MG/ML / diphenhydrAMINE hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1424850
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12815527
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
1424850
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Patient Education

Acetaminophen


Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever. Acetaminophen may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). Acetaminophen is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers). It works by changing the way the body senses pain and by cooling the body.
[Learn More]


Dextromethorphan


Dextromethorphan is used to temporarily relieve cough caused by the common cold, the flu, or other conditions. Dextromethorphan will relieve a cough but will not treat the cause of the cough or speed recovery. Dextromethorphan is in a class of medications called antitussives. It works by decreasing activity in the part of the brain that causes coughing.
[Learn More]


Diphenhydramine


Diphenhydramine is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. Diphenhydramine is also used to relieve cough caused by minor throat or airway irritation. Diphenhydramine is also used to prevent and treat motion sickness, and to treat insomnia (difficulty falling asleep or staying asleep). Diphenhydramine is also used to control abnormal movements in people who have early stage parkinsonian syndrome (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) or who are experiencing movement problems as a side effect of a medication. Diphenhydramine will relieve the symptoms of these conditions but will not treat the cause of the symptoms or speed recovery. Diphenhydramine should not be used to cause sleepiness in children. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
[Learn More]


Guaifenesin


Guaifenesin is used to relieve chest congestion. Guaifenesin may help control symptoms but does not treat the cause of symptoms or speed recovery. Guaifenesin is in a class of medications called expectorants. It works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.
[Learn More]


Phenylephrine


Phenylephrine is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Phenylephrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery. Phenylephrine is in a class of medications called nasal decongestants. It works by reducing swelling of the blood vessels in the nasal passages.
[Learn More]


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