Acetaminophen 200 mg / dextromethorphan hydrobromide 8 mg / diphenhydrAMINE 18.75 mg / guaiFENesin 35 mg / phenylephrine HCl 5 mg Oral Capsule
RxNorm 1664631

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 1664631 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: acetaminophen 200 mg / dextromethorphan hydrobromide 8 mg / diphenhydrAMINE 18.75 mg / guaiFENesin 35 mg / phenylephrine HCl 5 mg Oral Capsule.

The following semantic concepts and normalized strings are associated with this clinical entity:

SCD
Acetaminophen 200 mg / dextromethorphan hydrobromide 8 mg / diphenhydramine 18.75 mg / guaifenesin 35 mg / phenylephrine hydrochloride 5 mg Oral Capsule
Primary clinical definition
AUI:12349709
PSN
Acetaminophen 200 mg / dextromethorphan hydrobromide 8 mg / diphenhydrAMINE 18.75 mg / guaiFENesin 35 mg / phenylephrine HCl 5 mg Oral Capsule
AUI:7266963
TMSY
Acetaminophen 200 mg / dextromethorphan hydrobromide 8 mg / diphenhydrAMINE 18.75 mg / guaiFENesin 35 mg / phenylephrine hydrochloride 5 mg Oral Capsule
AUI:12383420
SY
APAP 200 mg / Dextromethorphan Hydrobromide 8 mg / Diphenhydramine 18.75 mg / Guaifenesin 35 mg / Phenylephrine Hydrochloride 5 mg Oral Capsule
AUI:7267021
TMSY
APAP 200 mg / Dextromethorphan Hydrobromide 8 mg / diphenhydrAMINE 18.75 mg / guaiFENesin 35 mg / Phenylephrine Hydrochloride 5 mg Oral Capsule
AUI:7267052

This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

SCD

Semantic Clinical Drug (SCD):
Acetaminophen 200 mg / dextromethorphan hydrobromide 8 mg / diphenhydramine 18.75 mg / guaifenesin 35 mg / phenylephrine hydrochloride 5 mg Oral Capsule
(Atom ID: 12349709)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
acetaminophen 200 MG / dextromethorphan hydrobromide 8 MG / diphenhydramine 18.75 MG / guaifenesin 35 MG / phenylephrine hydrochloride 5 MG Oral Capsule
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1664631
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12349709
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SCD
Semantic Clinical Drug (Ingredient + Strength + Dose Form)
Source Code
1664631
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN ACTIVATED
10/01/2024
Date the RxNorm atom was reactivated
RXN AI
{1020198} 8164
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{1664449} 102490
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{1664450} 5032
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{1664626} 3498
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{315255} 161
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AM
{1020198} 8163
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{1664449} 3289
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{1664450} 5032
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{1664626} 3498
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{315255} 161
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{1020198} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{1664449} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{1664450} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{1664626} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{315255} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN OBSOLETED
02/27/2024
Date the RxNorm atom became obsolete
RXN OBSOLETED
08/26/2025
Date the RxNorm atom became obsolete
RXTERM FORM
Cap
The RxTerm dose form name for this drug

PSN

Prescribable Name (PSN):
Acetaminophen 200 mg / dextromethorphan hydrobromide 8 mg / diphenhydrAMINE 18.75 mg / guaiFENesin 35 mg / phenylephrine HCl 5 mg Oral Capsule
(Atom ID: 7266963)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
acetaminophen 200 MG / dextromethorphan hydrobromide 8 MG / diphenhydrAMINE 18.75 MG / guaiFENesin 35 MG / phenylephrine HCl 5 MG Oral Capsule
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1664631
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
7266963
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
PSN
Prescribable Name (Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.)
Source Code
1664631
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

TMSY

Tall Man Lettering Synonym (TMSY):
Acetaminophen 200 mg / dextromethorphan hydrobromide 8 mg / diphenhydrAMINE 18.75 mg / guaiFENesin 35 mg / phenylephrine hydrochloride 5 mg Oral Capsule
(Atom ID: 12383420)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
acetaminophen 200 MG / dextromethorphan hydrobromide 8 MG / diphenhydrAMINE 18.75 MG / guaiFENesin 35 MG / phenylephrine hydrochloride 5 MG Oral Capsule
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1664631
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12383420
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
1664631
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

SY

Synonym (SY):
APAP 200 mg / Dextromethorphan Hydrobromide 8 mg / Diphenhydramine 18.75 mg / Guaifenesin 35 mg / Phenylephrine Hydrochloride 5 mg Oral Capsule
(Atom ID: 7267021)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
APAP 200 MG / Dextromethorphan Hydrobromide 8 MG / Diphenhydramine 18.75 MG / Guaifenesin 35 MG / Phenylephrine Hydrochloride 5 MG Oral Capsule
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1664631
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
7267021
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
1664631
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

TMSY

Tall Man Lettering Synonym (TMSY):
APAP 200 mg / Dextromethorphan Hydrobromide 8 mg / diphenhydrAMINE 18.75 mg / guaiFENesin 35 mg / Phenylephrine Hydrochloride 5 mg Oral Capsule
(Atom ID: 7267052)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
APAP 200 MG / Dextromethorphan Hydrobromide 8 MG / diphenhydrAMINE 18.75 MG / guaiFENesin 35 MG / Phenylephrine Hydrochloride 5 MG Oral Capsule
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1664631
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
7267052
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
1664631
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Patient Education

Acetaminophen


Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever. Acetaminophen may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). Acetaminophen is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers). It works by changing the way the body senses pain and by cooling the body.
[Learn More]


Dextromethorphan


Dextromethorphan is used to temporarily relieve cough caused by the common cold, the flu, or other conditions. Dextromethorphan will relieve a cough but will not treat the cause of the cough or speed recovery. Dextromethorphan is in a class of medications called antitussives. It works by decreasing activity in the part of the brain that causes coughing.
[Learn More]


Diphenhydramine


Diphenhydramine is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. Diphenhydramine is also used to relieve cough caused by minor throat or airway irritation. Diphenhydramine is also used to prevent and treat motion sickness, and to treat insomnia (difficulty falling asleep or staying asleep). Diphenhydramine is also used to control abnormal movements in people who have early stage parkinsonian syndrome (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) or who are experiencing movement problems as a side effect of a medication. Diphenhydramine will relieve the symptoms of these conditions but will not treat the cause of the symptoms or speed recovery. Diphenhydramine should not be used to cause sleepiness in children. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
[Learn More]


Guaifenesin


Guaifenesin is used to relieve chest congestion. Guaifenesin may help control symptoms but does not treat the cause of symptoms or speed recovery. Guaifenesin is in a class of medications called expectorants. It works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.
[Learn More]


Phenylephrine


Phenylephrine is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Phenylephrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery. Phenylephrine is in a class of medications called nasal decongestants. It works by reducing swelling of the blood vessels in the nasal passages.
[Learn More]


* Please review the disclaimer below.