Memantine and donepezil hydrochlorides titration pack 7 mg/10 mg (7), 14 mg/10 mg (7), 21 mg/10 mg (7), 28 mg/10 mg (7) Oral Capsule 28 Day Pack
RxNorm 1858970

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 1858970 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: memantine and donepezil hydrochlorides titration pack 7 mg/10 mg (7), 14 mg/10 mg (7), 21 mg/10 mg (7), 28 mg/10 mg (7) Oral Capsule 28 Day Pack.

The following semantic concepts and normalized strings are associated with this clinical entity:

SY
Memantine and donepezil hydrochlorides titration pack
AUI:8698898
PSN
Memantine and donepezil hydrochlorides titration pack 7 mg/10 mg (7), 14 mg/10 mg (7), 21 mg/10 mg (7), 28 mg/10 mg (7) Oral Capsule 28 Day Pack
AUI:8698899
GPCK
{7 (24 HR donepezil hydrochloride 10 mg / memantine hydrochloride 14 mg Extended Release Oral Capsule) / 7 (24 HR donepezil hydrochloride 10 mg / memantine hydrochloride 21 mg Extended Release Oral Capsule) / 7 (24 HR donepezil hydrochloride 10 mg / memantine hydrochloride 28 mg Extended Release Oral Capsule) / 7 (24 HR donepezil hydrochloride 10 mg / memantine hydrochloride 7 mg Extended Release Oral Capsule) } Pack
AUI:12372902

This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

SYPrescribable

Synonym (SY):
Memantine and donepezil hydrochlorides titration pack
(Atom ID: 8698898)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
memantine and donepezil hydrochlorides titration pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1858970
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
8698898
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
1858970
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

PSNPrescribable

Prescribable Name (PSN):
Memantine and donepezil hydrochlorides titration pack 7 mg/10 mg (7), 14 mg/10 mg (7), 21 mg/10 mg (7), 28 mg/10 mg (7) Oral Capsule 28 Day Pack
(Atom ID: 8698899)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
memantine and donepezil hydrochlorides titration pack 7 MG/10 MG (7), 14 MG/10 MG (7), 21 MG/10 MG (7), 28 MG/10 MG (7) Oral Capsule 28 Day Pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1858970
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
8698899
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
PSN
Prescribable Name (Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.)
Source Code
1858970
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

GPCKPrescribable

Generic Pack (GPCK):
{7 (24 HR donepezil hydrochloride 10 mg / memantine hydrochloride 14 mg Extended Release Oral Capsule) / 7 (24 HR donepezil hydrochloride 10 mg / memantine hydrochloride 21 mg Extended Release Oral Capsule) / 7 (24 HR donepezil hydrochloride 10 mg / memantine hydrochloride 28 mg Extended Release Oral Capsule) / 7 (24 HR donepezil hydrochloride 10 mg / memantine hydrochloride 7 mg Extended Release Oral Capsule) } Pack
(Atom ID: 12372902)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
{7 (24 HR donepezil hydrochloride 10 MG / memantine hydrochloride 14 MG Extended Release Oral Capsule) / 7 (24 HR donepezil hydrochloride 10 MG / memantine hydrochloride 21 MG Extended Release Oral Capsule) / 7 (24 HR donepezil hydrochloride 10 MG / memantine hydrochloride 28 MG Extended Release Oral Capsule) / 7 (24 HR donepezil hydrochloride 10 MG / memantine hydrochloride 7 MG Extended Release Oral Capsule) } Pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1858970
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12372902
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
GPCK
Generic Pack ({# (Ingredient + Strength + Dose Form) / # (Ingredient + Strength + Dose Form)} Pack)
Source Code
1858970
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN HUMAN DRUG
US
Drug available for use in Humans

Patient Education

Donepezil


Donepezil is used to treat dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and may cause changes in mood and personality) in people who have Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Donepezil is in a class of medications called cholinesterase inhibitors. It improves mental function (such as memory, attention, the ability to interact with others, speak, think clearly, and perform regular daily activities) by increasing the amount of a certain naturally occurring substance in the brain. Donepezil may improve the ability to think and remember or slow the loss of these abilities in people who have AD. However, donepezil will not cure AD or prevent the loss of mental abilities at some time in the future.
[Learn More]


Memantine


Memantine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Memantine is in a class of medications called NMDA receptor antagonists. It works by decreasing abnormal activity in the brain. Memantine may improve the ability to think and remember or may slow the loss of these abilities in people who have AD. However, memantine will not cure AD or prevent the loss of these abilities at some time in the future.
[Learn More]


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