100 daytime (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 nighttime (acetaminophen 250 mg / aspirin 250 mg / diphenhydrAMINE citrate 38 mg Oral Tablet) Kit
RxNorm 2047427

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 2047427 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: 100 daytime (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 nighttime (acetaminophen 250 mg / aspirin 250 mg / diphenhydrAMINE citrate 38 mg Oral Tablet) Kit.

The following semantic concepts and normalized strings are associated with this clinical entity:

PSN
100 daytime (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 nighttime (acetaminophen 250 mg / aspirin 250 mg / diphenhydrAMINE citrate 38 mg Oral Tablet) Kit
AUI:10276545
SY
100 daytime (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 nighttime (acetaminophen 250 mg / aspirin 250 mg / diphenhydramine citrate 38 mg Oral Tablet) Kit
AUI:10276544
TMSY
100 daytime (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 nighttime (acetaminophen 250 mg / aspirin 250 mg / diphenhydrAMINE citrate 38 mg Oral Tablet) Kit
AUI:10276650
GPCK
{100 (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 (acetaminophen 250 mg / aspirin 250 mg / diphenhydramine citrate 38 mg Oral Tablet) } Pack
AUI:12372917
TMSY
{100 (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 (acetaminophen 250 mg / aspirin 250 mg / diphenhydrAMINE citrate 38 mg Oral Tablet) } Pack
AUI:12379131

This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

PSN

Prescribable Name (PSN):
100 daytime (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 nighttime (acetaminophen 250 mg / aspirin 250 mg / diphenhydrAMINE citrate 38 mg Oral Tablet) Kit
(Atom ID: 10276545)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
100 daytime (acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet) / 24 nighttime (acetaminophen 250 MG / aspirin 250 MG / diphenhydrAMINE citrate 38 MG Oral Tablet) Kit
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2047427
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
10276545
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
PSN
Prescribable Name (Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.)
Source Code
2047427
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

SY

Synonym (SY):
100 daytime (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 nighttime (acetaminophen 250 mg / aspirin 250 mg / diphenhydramine citrate 38 mg Oral Tablet) Kit
(Atom ID: 10276544)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
100 daytime (acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet) / 24 nighttime (acetaminophen 250 MG / aspirin 250 MG / diphenhydramine citrate 38 MG Oral Tablet) Kit
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2047427
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
10276544
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
2047427
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

TMSY

Tall Man Lettering Synonym (TMSY):
100 daytime (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 nighttime (acetaminophen 250 mg / aspirin 250 mg / diphenhydrAMINE citrate 38 mg Oral Tablet) Kit
(Atom ID: 10276650)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
100 daytime (acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet) / 24 nighttime (acetaminophen 250 MG / aspirin 250 MG / diphenhydrAMINE citrate 38 MG Oral Tablet) Kit
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2047427
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
10276650
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
2047427
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

GPCK

Generic Pack (GPCK):
{100 (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 (acetaminophen 250 mg / aspirin 250 mg / diphenhydramine citrate 38 mg Oral Tablet) } Pack
(Atom ID: 12372917)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
{100 (acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet) / 24 (acetaminophen 250 MG / aspirin 250 MG / diphenhydramine citrate 38 MG Oral Tablet) } Pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2047427
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12372917
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
GPCK
Generic Pack ({# (Ingredient + Strength + Dose Form) / # (Ingredient + Strength + Dose Form)} Pack)
Source Code
2047427
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN ACTIVATED
11/28/2023
Date the RxNorm atom was reactivated
RXN HUMAN DRUG
US
Drug available for use in Humans
RXN OBSOLETED
07/31/2023
Date the RxNorm atom became obsolete

TMSY

Tall Man Lettering Synonym (TMSY):
{100 (acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg Oral Tablet) / 24 (acetaminophen 250 mg / aspirin 250 mg / diphenhydrAMINE citrate 38 mg Oral Tablet) } Pack
(Atom ID: 12379131)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
{100 (acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet) / 24 (acetaminophen 250 MG / aspirin 250 MG / diphenhydrAMINE citrate 38 MG Oral Tablet) } Pack
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2047427
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12379131
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
2047427
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Patient Education

Acetaminophen


Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever. Acetaminophen may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). Acetaminophen is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers). It works by changing the way the body senses pain and by cooling the body.
[Learn More]


Aspirin


Prescription aspirin is used to relieve the symptoms of rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), osteoarthritis (arthritis caused by breakdown of the lining of the joints), systemic lupus erythematosus (condition in which the immune system attacks the joints and organs and causes pain and swelling) and certain other rheumatologic conditions (conditions in which the immune system attacks parts of the body). Nonprescription aspirin is used to reduce fever and to relieve mild to moderate pain from headaches, menstrual periods, arthritis, toothaches, and muscle aches. Nonprescription aspirin is also used to prevent heart attacks in people who have had a heart attack in the past or who have angina (chest pain that occurs when the heart does not get enough oxygen). Nonprescription aspirin is also used to reduce the risk of death in people who are experiencing or who have recently experienced a heart attack. Nonprescription aspirin is also used to prevent ischemic strokes (strokes that occur when a blood clot blocks the flow of blood to the brain) or mini-strokes (strokes that occur when the flow of blood to the brain is blocked for a short time) in people who have had this type of stroke or mini-stroke in the past. Aspirin will not prevent hemorrhagic strokes (strokes caused by bleeding in the brain). Aspirin is in a group of medications called salicylates. It works by stopping the production of certain natural substances that cause fever, pain, swelling, and blood clots. Aspirin is also available in combination with other medications such as antacids, pain relievers, and cough and cold medications. This monograph only includes information about the use of aspirin alone. If you are taking a combination product, read the information on the package or prescription label or ask your doctor or pharmacist for more information.
[Learn More]


Diphenhydramine


Diphenhydramine is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. Diphenhydramine is also used to relieve cough caused by minor throat or airway irritation. Diphenhydramine is also used to prevent and treat motion sickness, and to treat insomnia (difficulty falling asleep or staying asleep). Diphenhydramine is also used to control abnormal movements in people who have early stage parkinsonian syndrome (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) or who are experiencing movement problems as a side effect of a medication. Diphenhydramine will relieve the symptoms of these conditions but will not treat the cause of the symptoms or speed recovery. Diphenhydramine should not be used to cause sleepiness in children. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
[Learn More]


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