RxNorm 6851

MTX - methotrexate

RxNorm Semantic Concepts

RxNorm semantic concepts for the RxCUI 6851 unique identifier include: methotrexate (12251041), MTX - methotrexate (11437480), Amethopterin (222753), Methotrexate (222741), Methotrexate (substance) (222767), Product containing methotrexate (medicinal product) (9259654) and Methotrexate-containing product (10806990).

RxNorm Atom ID: 12251041 - Ingredient
methotrexate

RXCUI:
6851 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
12251041 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
methotrexate - Description of concept identifier
Term Type (TTY):
IN - Term type in source with name and description
Term Type Name:
Ingredient - Name of term type in source
Term Type Description:
A compound or moiety that gives the drug its distinctive clinical properties. Ingredients generally use the United States Adopted Name (USAN). - Description of term type in source
Code:
6851 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
4096 - Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
YL5FZ2Y5U1 - METHOTREXATE (n1c(c2nc(CN(c3ccc(C(N[C@H](C(=O)O)CCC(=O)O)=O)cc3)C)cnc2nc1N)N) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
RXNORM - Concept source abbreviation
Source Name:
RxNorm Vocabulary - The official name for a source
Source Version:
20AA_240506F - The source version
Source Date:
May 06, 2024 - RxNorm data last updated
Source License Contact:
RxNorm Customer Service

U.S. National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
(888) FIND-NLM

[email protected]
https://www.nlm.nih.gov/research/umls/rxnorm/ - The source license contact information
Source Content Contact:
RxNorm Customer Service

U.S. National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
(888) FIND-NLM

[email protected]
https://www.nlm.nih.gov/research/umls/rxnorm/ - The source content contact information
Source Short Name:
RxNorm work done by the National Library of Medicine - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 11437480 - Synonym
MTX - methotrexate

RXCUI:
6851 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
11437480 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
MTX - methotrexate - Description of concept identifier
Term Type (TTY):
SY - Term type in source with name and description
Term Type Name:
Synonym - Name of term type in source
Term Type Description:
Synonym of another TTY, given for clarity. - Description of term type in source
Code:
387381009 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
YL5FZ2Y5U1 - METHOTREXATE (n1c(c2nc(CN(c3ccc(C(N[C@H](C(=O)O)CCC(=O)O)=O)cc3)C)cnc2nc1N)N) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
May 06, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 222753 - Synonym
Amethopterin

RXCUI:
6851 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
222753 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
Amethopterin - Description of concept identifier
Term Type (TTY):
SY - Term type in source with name and description
Term Type Name:
Synonym - Name of term type in source
Term Type Description:
Synonym of another TTY, given for clarity. - Description of term type in source
Code:
387381009 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
YL5FZ2Y5U1 - METHOTREXATE (n1c(c2nc(CN(c3ccc(C(N[C@H](C(=O)O)CCC(=O)O)=O)cc3)C)cnc2nc1N)N) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
May 06, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 222741 - Designated preferred name
Methotrexate

RXCUI:
6851 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
222741 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
Methotrexate - Description of concept identifier
Term Type (TTY):
PT - Term type in source with name and description
Term Type Name:
Designated preferred name - Name of term type in source
Term Type Description:
- Description of term type in source
Code:
387381009 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
YL5FZ2Y5U1 - METHOTREXATE (n1c(c2nc(CN(c3ccc(C(N[C@H](C(=O)O)CCC(=O)O)=O)cc3)C)cnc2nc1N)N) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
May 06, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 222767 - Full form of descriptor
Methotrexate (substance)

RXCUI:
6851 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
222767 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
Methotrexate (substance) - Description of concept identifier
Term Type (TTY):
FN - Term type in source with name and description
Term Type Name:
Full form of descriptor - Name of term type in source
Term Type Description:
- Description of term type in source
Code:
387381009 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
YL5FZ2Y5U1 - METHOTREXATE (n1c(c2nc(CN(c3ccc(C(N[C@H](C(=O)O)CCC(=O)O)=O)cc3)C)cnc2nc1N)N) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
May 06, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 9259654 - Full form of descriptor
Product containing methotrexate (medicinal product)

RXCUI:
6851 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
9259654 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
Product containing methotrexate (medicinal product) - Description of concept identifier
Term Type (TTY):
FN - Term type in source with name and description
Term Type Name:
Full form of descriptor - Name of term type in source
Term Type Description:
- Description of term type in source
Code:
68887009 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
YL5FZ2Y5U1 - METHOTREXATE (n1c(c2nc(CN(c3ccc(C(N[C@H](C(=O)O)CCC(=O)O)=O)cc3)C)cnc2nc1N)N) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
May 06, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 10806990 - Designated preferred name
Methotrexate-containing product

RXCUI:
6851 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
10806990 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
Methotrexate-containing product - Description of concept identifier
Term Type (TTY):
PT - Term type in source with name and description
Term Type Name:
Designated preferred name - Name of term type in source
Term Type Description:
- Description of term type in source
Code:
68887009 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
YL5FZ2Y5U1 - METHOTREXATE (n1c(c2nc(CN(c3ccc(C(N[C@H](C(=O)O)CCC(=O)O)=O)cc3)C)cnc2nc1N)N) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
May 06, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

* This product uses publicly available data courtesy of the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Patient Education

Methotrexate


Methotrexate is used to treat severe psoriasis (a skin disease in which red, scaly patches form on some areas of the body) that cannot be controlled by other treatments. Methotrexate is also used along with rest, physical therapy, and sometimes other medications to treat severe active rheumatoid arthritis (RA; a condition in which the body attacks its own joints, causing pain, swelling, and loss of function) that cannot be controlled by certain other medications. Methotrexate is also used to treat certain types of cancer including cancers that begin in the tissues that form around a fertilized egg in the uterus, breast cancer, lung cancer, certain cancers of the head and neck, certain types of lymphoma, and leukemia (cancer that begins in the white blood cells). Methotrexate is in a class of medications called antimetabolites. Methotrexate treats cancer by slowing the growth of cancer cells. Methotrexate treats psoriasis by slowing the growth of skin cells to stop scales from forming. Methotrexate may treat rheumatoid arthritis by decreasing the activity of the immune system.
[Learn More]


Methotrexate Injection


Methotrexate injection is used alone or in combination with other medications: to treat certain types of acute lymphocytic leukemia (ALL) in adults and children; to treat or prevent meningeal leukemia (cancer in the covering of the spinal cord and brain) in adults and children; to treat certain types of non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection) in adults and children; to treat osteosarcoma (cancer that forms in bones) after surgery to remove the tumor in adults and children; to treat cutaneous T-cell lymphoma (CTCL, a group of cancers of the immune system that first appear as skin rashes); to treat breast cancer in adults; to treat certain cancers of the head and neck in adults; to treat gestational trophoblastic tumors (a type of tumor that forms inside a woman's uterus when pregnant) in adults; to treat rheumatoid arthritis (RA; a condition in which the body attacks its own joints, causing pain, swelling, and loss of function) in adults; to treat polyarticular juvenile idiopathic arthritis (pJIA; a type of childhood arthritis that affects five or more joints during the first six months of the condition, causing pain, swelling, and loss of function) in children; and to treat severe psoriasis (a skin disease in which red, scaly patches form on some areas of the body) in adults. Methotrexate is in a class of medications called antimetabolites. Methotrexate treats cancer by slowing the growth of cancer cells. Methotrexate treats psoriasis by slowing the growth of skin cells to stop scales from forming. Methotrexate may treat rheumatoid arthritis and polyarticular juvenile idiopathic arthritis by decreasing the activity of the immune system.
[Learn More]


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