UNII YL5FZ2Y5U1

METHOTREXATE

UNII Information

Unique Ingredient Identifier: YL5FZ2Y5U1
The Unique Ingredient Identifier (UNII) is a unique alphanumeric code assigned to a specific substance or ingredient by the FDA (Food and Drug Administration). UNII codes are non-proprietary, free, unique, unambiguous and nonsemantic. Each UNII code consists of 10 characters with both letters and numbers. The first two characters represent the source of the substance while the remaining eight characters represent the specific substance. UNII codes are primarily used to identify and track substances in several drug databases and regulatory documents related to drugs, biologics, and medical devices.
Formula: 926
Molecular Formula, total atoms represented as a molecular structure in a UNII description.
Preferred Substance Name: METHOTREXATE
The Preferred Substance Name (PSN) is the official or preferred name of a substance or ingredient. The preferred name provides a standardized and consistent name for each substance is used in the UNII code system. The preferred name may differ from other names also commonly used to refer the same substance. The PSN is usually the name used by regulatory agencies like the FDA.
SMILES: C20H22N8O5
The Simplified Molecular Input Line Entry System or SMILES is a format used to represent and describe the molecular structure of a substance or ingredient. SMILES uses a series of alphanumeric characters to represent the atoms and bonds in a molecule in conjunction with other symbols and operators to indicate the arrangement and connectivity of the atoms.
Registry Number: 59-05-2
The Registry Number is the unique numerical identifiers assigned to a substance or ingredient by the Chemical Abstracts Service (CAS). The CAS registry number is a used and recognized standard identifier by many industries and regulatory agencies. The Registry Number facilitates cross-referencing substances between different databases that may use different naming conventions or identifiers.
NCI Thesaurus Concept Code: C642
The NCI Thesaurus give reference terminology for many systems. The code includes vocabulary for clinical care, translational research, basic research, public information and administrative activities.
UNII to RxNorm Crosswalk: 6851 (RXCUI)
The RxNorm Ingredient Concept Code is the numeric code assigned to a specific substance or ingredient by the National Library of Medicine's RxNorm system. By including the RxNorm code in the UNII code system it is possible to crossover UNII codes to RxNom.
PubChem Compound ID: 126941
The PubChem Compound ID is a unique identifier for a specific substance or ingredient in the PubChem database which is the largest collection of freely accessible chemical information by the National Center for Biotechnology Information. The PubChem database is a resource for drug discovery, development, chemical research, and other applications.
ITIS TSN: DTXSID4020822
The Taxonomic Serial Number is a unique identifier for a specific species of organism in the Integrated Taxonomic Information System. The ITIS is a comprehensive database of taxonomic information on plants, animals, fungi, and microbes, maintained by a partnership of several US government agencies.
Ingredient Type: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Substance Type: INGREDIENT SUBSTANCE
The International Organization for Standardization - ISO 11238 substance type is used as a data element in the UNII code system to provide additional information about the type of substance being identified.

UNII Synonyms and Mappings

The following synonyms and mappings provide alternative ways to refer to the same substance or ingredient. Synonyms may include different names or spellings, alternate chemical names, trade names, or other common names.

  • (2S)-2-((4-(((2,4-DIAMINOPTERIDIN-6-YL)METHYL)(METHYL)AMINO)BENZOYL)AMINO)PENTANEDIOIC ACID - Systematic Name (chemical and taxonomic names)
  • ADX-2191 - Code
  • AMETHOPTERIN - Common Name
  • CL 14377 - Code
  • CL-14377 - Code
  • JYLAMVO - Brand/Trade Name
  • METHOTREXATE - Name identified as having official status
  • METHOTREXATE [EP MONOGRAPH] - Common Name
  • METHOTREXATE [HSDB] - Common Name
  • METHOTREXATE [IARC] - Common Name
  • METHOTREXATE [INCI] - Common Name
  • METHOTREXATE [INN] - Common Name
  • METHOTREXATE [JAN] - Common Name
  • METHOTREXATE [MART.] - Common Name
  • METHOTREXATE [MI] - Common Name
  • METHOTREXATE [ORANGE BOOK] - Common Name
  • METHOTREXATE [USAN] - Common Name
  • METHOTREXATE [USP IMPURITY] - Common Name
  • METHOTREXATE [USP MONOGRAPH] - Common Name
  • METHOTREXATE [USP-RS] - Common Name
  • METHOTREXATE [VANDF] - Common Name
  • METHOTREXATE [WHO-DD] - Common Name
  • METHOTREXATE [WHO-IP] - Common Name
  • METHOTREXATUM [WHO-IP LATIN] - Common Name
  • METHYLAMINOPTERIN - Common Name
  • MTX - Common Name
  • NSC-740 - Code
  • R-9985 - Code
  • RASUVO - Brand/Trade Name
  • REDITREX - Brand/Trade Name
  • XATMEP - Brand/Trade Name

UNII Resources

Common Chemistry
CAS Common Chemistry is an open community resource of the American Chemical Society for accessing chemical information. The chemical information in the CAS database is curated by expert scientists and includes information of common and frequently regulated chemicals and information applicable to high school and undergraduate chemistry classes.
Inxight Drugs
The National Center for Advancing Translational Sciences (NCATS) Inxight Drugs database has a comprehensive drug development information. The NCATS Inxight Drugs includes manually curated data provided by private companies and FDA. The database has marketing and regulatory status information, rigorous drug ingredient definitions, biological activity, clinical use, etc.
DailyMed Regulated Products
The National Library of Medicine DailyMed is a searchable database that includes the most recent product labeling information submitted to the FDA by private companies.
NCATS GSRS Full Record
The Global Substance Registration System (GSRS) was designed to facilitate global monitoring of human and animal medicinal, food, tobacco, and cosmetic products. GSRS includes unique substance identifiers consistent with the ISO 11238 standard.
NCI Thesaurus
NCI Thesaurus (NCIt) by the National Cancer Institute provides reference terminology for clinical care, translational and basic research, and public information and administrative activities.
PubChem
The PubChem database by the National Library of Medicine includes the chemical structures of small organic molecules and information on their biological activities.

UNII Crossover to NDC Codes

This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory:

NDC Proprietary Name Non-Proprietary Name Dosage Form Route Name Company Name Status
0054-4550Proprietary Name: Methotrexate Sodium Methotrexate SodiumTabletOralHikma Pharmaceuticals Usa Inc.ACTIVE
0054-8550Proprietary Name: Methotrexate Sodium Methotrexate SodiumTabletOralHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9367Proprietary Name: Methotrexate MethotrexateInjection, Powder, Lyophilized, For SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9516Proprietary Name: Methotrexate MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9517Proprietary Name: Methotrexate MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9518Proprietary Name: Methotrexate MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9519Proprietary Name: Methotrexate MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9830Proprietary Name: Methotrexate MethotrexateInjection, Powder, Lyophilized, For SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0378-0014Proprietary Name: Methotrexate MethotrexateTabletOralMylan Pharmaceuticals Inc.ACTIVE
0555-0572Proprietary Name: Methotrexate MethotrexateTabletOralTeva Pharmaceuticals Usa, Inc.ACTIVE
0703-3671Proprietary Name: Methotrexate MethotrexateInjection, SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousTeva Parenteral Medicines, Inc.ACTIVE
0703-3675Proprietary Name: Methotrexate MethotrexateInjection, SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousTeva Parenteral Medicines, Inc.ACTIVE
0703-3678Proprietary Name: Methotrexate MethotrexateInjection, SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousTeva Parenteral Medicines, Inc.ACTIVE
0703-3678Proprietary Name: Methotrexate MethotrexateInjection, SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousTeva Parenteral Medicines, Inc.ACTIVE
0904-7141Proprietary Name: Methotrexate MethotrexateTabletOralMajor PharmaceuticalsACTIVE
16729-277Proprietary Name: Methotrexate MethotrexateInjectionIntra-arterial; Intramuscular; Intrathecal; IntravenousAccord Healthcare, Inc.ACTIVE
16729-486Proprietary Name: Methotrexate MethotrexateTabletOralAccord Healthcare Inc.ACTIVE
42291-505Proprietary Name: Methotrexate MethotrexateTabletOralAvkareACTIVE
47335-235Proprietary Name: Methotrexate Methotrexate SodiumTabletOralSun Pharmaceutical Industries, Inc.ACTIVE
50090-2345Proprietary Name: Methotrexate A-s Medication SolutionsINACTIVATED
50090-3418Proprietary Name: Methotrexate Methotrexate SodiumTabletOralA-s Medication SolutionsACTIVE
50090-5457Proprietary Name: Methotrexate MethotrexateTabletOralA-s Medication SolutionsACTIVE
50268-527Proprietary Name: Methotrexate MethotrexateTabletOralAvpakACTIVE
51079-670Proprietary Name: Methotrexate MethotrexateTabletOralMylan Institutional Inc.ACTIVE
51285-366Proprietary Name: Trexall MethotrexateTablet, Film CoatedOralTeva Women's Health, Inc.ACTIVE
51285-367Proprietary Name: Trexall MethotrexateTablet, Film CoatedOralTeva Women's Health, Inc.ACTIVE
51285-368Proprietary Name: Trexall MethotrexateTablet, Film CoatedOralTeva Women's Health, Inc.ACTIVE
51285-369Proprietary Name: Trexall MethotrexateTablet, Film CoatedOralTeva Women's Health, Inc.ACTIVE
51407-121Proprietary Name: Methotrexate MethotrexateTabletOralGolden State Medical Supply, Inc.ACTIVE
52652-2001Proprietary Name: Xatmep MethotrexateSolutionOralAzurity Pharmaceuticals, Inc.ACTIVE
54436-010Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-012Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-015Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-017Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-020Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-022Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-025Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
59137-505Proprietary Name: Rasuvo MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-510Proprietary Name: Rasuvo MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-515Proprietary Name: Rasuvo MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-520Proprietary Name: Rasuvo MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-525Proprietary Name: Rasuvo MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-530Proprietary Name: Rasuvo MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-535Proprietary Name: Rasuvo MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-540Proprietary Name: Rasuvo MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-550Proprietary Name: Rasuvo MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59651-182Proprietary Name: Methotrexate MethotrexateTabletOralAurobindo Pharma LimitedACTIVE
61703-124Proprietary Name: Methotrexate MethotrexateInjection, SolutionIntramuscular; Intrathecal; Intravenous; SubcutaneousHospira, Inc.ACTIVE
61703-350Proprietary Name: Methotrexate MethotrexateInjection, SolutionIntramuscular; Intravenous; SubcutaneousHospira, Inc.ACTIVE
61703-350Proprietary Name: Methotrexate MethotrexateInjection, SolutionIntramuscular; Intravenous; SubcutaneousHospira, Inc.ACTIVE
62135-772Proprietary Name: Methotrexate MethotrexateTabletOralChartwell Rx, LlcACTIVE
63323-122Proprietary Name: Methotrexate Methotrexate SodiumInjection, Powder, Lyophilized, For SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousFresenius Kabi Usa, LlcACTIVE
63323-123Proprietary Name: Methotrexate Methotrexate SodiumInjection, SolutionIntra-arterial; Intramuscular; IntravenousFresenius Kabi Usa, LlcACTIVE
68382-775Proprietary Name: Methotrexate MethotrexateTabletOralZydus Pharmaceuticals Usa Inc.ACTIVE
69238-1423Proprietary Name: Methotrexate MethotrexateTabletOralAmneal Pharmaceuticals Ny LlcACTIVE
70518-1398Proprietary Name: Methotrexate MethotrexateTabletOralRemedyrepack Inc.ACTIVE
70518-3263Proprietary Name: Methotrexate MethotrexateTabletOralRemedyrepack Inc.ACTIVE
70518-3672Proprietary Name: Methotrexate MethotrexateTabletOralRemedyrepack Inc.ACTIVE
70518-3777Proprietary Name: Methotrexate MethotrexateTabletOralRemedyrepack Inc.ACTIVE
70771-1058Proprietary Name: Methotrexate MethotrexateTabletOralZydus Lifesciences LimitedACTIVE
71335-1118Proprietary Name: Methotrexate Bryant Ranch PrepackINACTIVATED
71335-1772Proprietary Name: Methotrexate MethotrexateTabletOralBryant Ranch PrepackACTIVE
71335-2221Proprietary Name: Methotrexate MethotrexateTabletOralBryant Ranch PrepackACTIVE
72162-2174Proprietary Name: Methotrexate Methotrexate SodiumTabletOralBryant Ranch PrepackACTIVE
81927-204Proprietary Name: Jylamvo MethotrexateSolutionOralShorla Oncology Inc.ACTIVE