Inactive / Discontinued
METHOTREXATE
UNII YL5FZ2Y5U1
Substance Identification & Data
This profile provides standardized clinical and technical data for Methotrexate, uniquely identified by the FDA Unique Ingredient Identifier (UNII) YL5FZ2Y5U1.
Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 59-05-2 and the RxNorm Concept ID (RxCUI) 6851. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.
Detailed Substance Profile
Preferred Name
METHOTREXATE
Official standardized name for this substance within the FDA UNII nomenclature system.
Molecular Formula
YL5FZ2Y5U1
The specific atomic composition represented as a molecular structure string.
InChIKey
C20H22N8O5 International Chemical Identifier digital signature for unique molecular identification.
SMILES String
FBOZXECLQNJBKD-ZDUSSCGKSA-N Line notation for describing the chemical structure and connectivity of atoms.
INN ID
926
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
n1c(c2nc(CN(c3ccc(C(N[C@H](C(=O)O)CCC(=O)O)=O)cc3)C)cnc2nc1N)N
Synonyms and Nomenclature
This section provides a complete list of nomenclature and identifier mappings for Methotrexate. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.
FDA Official Name
METHOTREXATE
Common Names & Synonyms
AMETHOPTERIN
METHOTREXATE [EP MONOGRAPH]
METHOTREXATE [HSDB]
METHOTREXATE [IARC]
METHOTREXATE [INN]
METHOTREXATE [JAN]
METHOTREXATE [MART.]
METHOTREXATE [MI]
METHOTREXATE [ORANGE BOOK]
METHOTREXATE [USAN]
METHOTREXATE [USP IMPURITY]
METHOTREXATE [USP MONOGRAPH]
METHOTREXATE [USP-RS]
METHOTREXATE [VANDF]
METHOTREXATE [WHO-DD]
METHOTREXATE [WHO-IP]
METHOTREXATUM [WHO-IP LATIN]
METHYLAMINOPTERIN
MTX
Brand / Trade Names
JYLAMVO
RASUVO
REDITREX
XATMEP
Systematic Nomenclature
(2S)-2-((4-(((2,4-DIAMINOPTERIDIN-6-YL)METHYL)(METHYL)AMINO)BENZOYL)AMINO)PENTANEDIOIC ACID
Technical Codes
ADX-2191
CL 14377
CL-14377
NSC-740
R-9985
NDC Products Containing METHOTREXATE
This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory:
