Niacin 500 mg / simvastatin 20 mg 24HR Extended Release Oral Tablet
RxNorm 761909
Concept Hierarchy & Relationship Mapping
RxNorm Concept Unique Identifier (RxCUI) 761909 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: niacin 500 mg / simvastatin 20 mg 24HR Extended Release Oral Tablet.
The following semantic concepts and normalized strings are associated with this clinical entity:
This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.
SCD
Semantic Clinical Drug (SCD):
24 HR niacin 500 mg / simvastatin 20 mg Extended Release Oral Tablet
(Atom ID: 12347565)
SY
Synonym (SY):
24 HR nicotinic acid 500 mg / Simvastatin 20 mg Extended Release Oral Tablet
(Atom ID: 6358156)
SY
Synonym (SY):
24 HR vit-B3 500 mg / Simvastatin 20 mg Extended Release Oral Tablet
(Atom ID: 6355522)
SY
Synonym (SY):
24 HR vitamin B3 500 mg / Simvastatin 20 mg Extended Release Oral Tablet
(Atom ID: 6357526)
SY
Synonym (SY):
Niacin 500 mg / simvastatin 20 mg 24 HR Extended Release Oral Tablet
(Atom ID: 6353628)
PSN
Prescribable Name (PSN):
Niacin 500 mg / simvastatin 20 mg 24HR Extended Release Oral Tablet
(Atom ID: 6360386)
PT
Designated preferred name (PT):
Niacin 500 mg and simvastatin 20 mg prolonged-release oral tablet
(Atom ID: 11437751)
SY
Synonym (SY):
Nicotinic acid 500 mg and simvastatin 20 mg prolonged-release oral tablet
(Atom ID: 11437768)
FN
Full form of descriptor (FN):
Product containing precisely nicotinic acid 500 mg and simvastatin 20 mg/1 each prolonged-release oral tablet (clinical drug)
(Atom ID: 11440396)
Patient Education
Niacin
Niacin is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in your blood and to increase the amount of high density lipoprotein (HDL; ''good cholesterol''). Niacin can be used in a number of situations including the following: alone or in combination with other medications, such as HMG-CoA inhibitors (statins) or bile acid-binding resins; to decrease the risk of another heart attack in patients with high cholesterol who have had a heart attack; to prevent worsening of atherosclerosis (buildup of cholesterol and fats along the walls of the blood vessels) in patients with high cholesterol and coronary artery disease; to reduce the amount of triglycerides (other fatty substances) in the blood in patients with very high triglycerides who are at risk of pancreatic disease (conditions affecting the pancreas, a gland that produces fluid to break down food and hormones to control blood sugar). Niacin is also used to prevent and treat pellagra (niacin deficiency), a disease caused by inadequate diet and other medical problems. Niacin is a B-complex vitamin. At therapeutic doses, niacin is a cholesterol-lowering medication. Results of a clinical study in people with heart disease and well-controlled cholesterol levels that compared people who took niacin and simvastatin with people who took simvastatin alone and found similar results for the two groups in the rate of heart attacks or strokes. Taking niacin along with simvastatin or lovastatin also has not been shown to reduce the risk of heart disease or death compared with the use of niacin, simvastatin, or lovastatin alone. Talk to your doctor if you have questions about the risks and benefits of treating increased amounts of cholesterol in your blood with niacin and other medications.
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Simvastatin
Simvastatin is used together with diet, weight-loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease. Simvastatin is also used to decrease the amount of fatty substances such as low-density lipoprotein (LDL) cholesterol (''bad cholesterol'') and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL) cholesterol (''good cholesterol'') in the blood. Simvastatin may also be used to decrease the amount of cholesterol and other fatty substances in the blood in children and teenagers 10 to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally). Simvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats with simvastatin has been shown to prevent heart disease, angina (chest pain), strokes, and heart attacks.
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