ESTRADIOL
UNII 4TI98Z838E

Substance Identification & Data

This profile provides standardized clinical and technical data for Estradiol, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 4TI98Z838E.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 50-28-2 and the RxNorm Concept ID (RxCUI) 4083. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
4TI98Z838E
CAS Registry Number
50-28-2
RxNorm Concept ID

Detailed Substance Profile

Preferred Name
ESTRADIOL
Official standardized name for this substance within the FDA UNII nomenclature system.
Molecular Formula
4TI98Z838E
The specific atomic composition represented as a molecular structure string.
InChIKey
C18H24O2
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
VOXZDWNPVJITMN-ZBRFXRBCSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
406
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
[C@]12([C@]([C@@]3(CCc4c([C@]3(CC1)[H])ccc(O)c4)[H])(CC[C@@H]2O)[H])C

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Estradiol. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ESTRADIOL

Common Names & Synonyms

17 .BETA.-ESTRADIOL
17.BETA.-ESTRADIOL
17-.BETA.-OESTRADIOL
17BETA-ESTRADIOL
17-BETA-OESTRADIOL
ACTIVELLA COMPONENT ESTRADIOL
ANGELIQ COMPONENT ESTRADIOL
BIJUVA COMPONENT ESTRADIOL
CLIMARA PRO COMPONENT ESTRADIOL
COMBIPATCH COMPONENT ESTRADIOL
E2
ESTRA-1,3,5(10)-TRIENE-3,17-DIOL (17.BETA.)-
ESTRADIOL [GREEN BOOK]
ESTRADIOL [HSDB]
ESTRADIOL [INN]
ESTRADIOL [JAN]
ESTRADIOL [MI]
ESTRADIOL [ORANGE BOOK]
ESTRADIOL [USP MONOGRAPH]
ESTRADIOL [USP-RS]
ESTRADIOL [VANDF]
ESTRADIOL [WHO-DD]
ESTRADIOL 17-BETA
ESTRADIOL 17-BETA [VANDF]
ESTRADIOL ANHYDROUS
ESTRADIOL BENZOATE IMPURITY A [EP IMPURITY]
ESTRADIOL IMPURITY A [IP]
ESTRADIOL VALERATE IMPURITY A [EP IMPURITY]
ESTRADIOL VALERATE METABOLITE E2
ETHINYLESTRADIOL IMPURITY D [EP IMPURITY]
OESTRADIOL
PREFEST COMPONENT ESTRADIOL

Brand / Trade Names

AERODIOL
ALORA
CLIMARA
DIVIGEL
ELESTRIM
ESCLIM
ESTRACE
ESTRADERM
ESTRING
ESTROGEL
EVAMIST
FEMPATCH
GYNODIOL
IMVEXXY
INNOFEM
MENOSTAR
ORIAHNN COMPONENT ESTRADIOL
VAGIFEM
VIVELLE

Systematic Nomenclature

(+)-3,17.BETA.-ESTRADIOL
13.BETA.-METHYL-1,3,5(10)-GONATRIENE-3,17.BETA.-OL
3,17.BETA.-DIHYDROXYESTRA-1,3,5(10)-TRIENE
ESTRA-1,3,5(10)-TRIENE-3,17.BETA.-DIOL

Technical Codes

NSC-20293
NSC-9895
S 21400
S21400
S21400 (INTRANASAL)
WC3011
WC-3011

NDC Products Containing ESTRADIOL

This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory: