Vaxneuvance Injection, Suspension
NDC Package 0006-4329-03

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. NDC HCPCS Crosswalk
    3. Other Packages
    4. Frequently Asked Questions

Package Information

Vaxneuvance (pneumococcal 15-valent conjugate vaccine crm197 protein adsorbed) injection is vAXNEUVANCE™ is indicated for active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F and 33F in adults 18 years of age and older. This formulation utilizes a injection, suspension delivery system. Marketed by Merck Sharp & Dohme Llc, this product is identified by NDC 0006-4329 and is authorized under FDA application BLA125741.

Identification & Billing

NDC Package Code
0006-4329-03
Package Description
10 SYRINGE, GLASS in 1 CARTON / .5 mL in 1 SYRINGE, GLASS (0006-4329-01)
Product Code
0006-4329
11-Digit Billing Format
00006432903
Billing Unit
ML - Billing unit of "milliliter" is used when a product is measured by its liquid volume.

Clinical Specifications

Proprietary Name
Vaxneuvance
Non-Proprietary Name
Pneumococcal 15-valent Conjugate Vaccine Crm197 Protein Adsorbed
Substance Name
Corynebacterium Diphtheriae Crm197 Protein; Streptococcus Pneumoniae Type 1 Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 14 Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 18c Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 19a Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 19f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 22f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 23f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 3 Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 33f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 4 Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 5 Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 6a Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 6b Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen; Streptococcus Pneumoniae Type 9v Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen
Dosage Form
Injection, Suspension - A liquid preparation, suitable for injection, which consists of solid particles dispersed throughout a liquid phase in which the particles are not soluble. It can also consist of an oil phase dispersed throughout an aqueous phase, or vice-versa.
Administration Route
Intramuscular - Administration within a muscle.
Active Ingredient(s)
Pharmacologic Class
Usage Information
VAXNEUVANCE™ is indicated for active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F and 33F in adults 18 years of age and older.

Regulatory & Marketing

Labeler Name
Merck Sharp & Dohme Llc
Product Type
Vaccine
FDA Application #
BLA125741
Marketing Category
BLA - A product marketed under an approved Biologic License Application.
Start Marketing Date
07-16-2021
Listing Expiration
12-31-2027
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Billing & HCPCS Mapping

To facilitate insurance claims and reimbursement, this drug package is mapped to specific HCPCS administrative codes. This crosswalk aligns clinical data with the billing standards used in ASP (Average Sales Price), AWP, and OPPS payment systems. Use the cards below to identify the correct billable units for provider claims.

90671
Source: AWP
PCV15 VACCINE IM
HCPCS Dosage 1 EA
Units / Pkg 10

Note for Medical Coders: These mappings are synthesized from various CMS datasets including OPPS, PrEP, and DAC (Data Analysis and Coding) contractors. Always confirm unit conversions against the current quarter's pricing files before final submission.

* Please review the full disclaimer at the bottom of this page.

Other Available Packages

The following commercial packages are registered under the same Product NDC (0006-4329). Click a package code to view its specific billing and regulatory data.

0006-4329-02
1 SYRINGE, GLASS in 1 CARTON / .5 mL in 1 SYRINGE, GLASS (0006-4329-01)

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 0006-4329-03 identifies a specific commercial package of 10 syringe, glass in 1 carton / .5 ml in 1 syringe, glass (0006-4329-01) of Vaxneuvance, a vaccine label labeled by Merck Sharp & Dohme Llc. This injection, suspension is formulated for intramuscular use and contains corynebacterium diphtheriae crm197 protein; streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 19a capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 22f capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 3 capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 33f capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 5 capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 6a capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 7f capsular polysaccharide diphtheria crm197 protein conjugate antigen; streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Merck Sharp & Dohme Llc on July 16, 2021. The current certification is valid through December 31, 2027.

How is this Merck Sharp & Dohme Llc product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 00006432903. Quantities are measured in per "ml or milliliter", products billed per milliliter are usually products measured by liquid volume.. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (4-4-2)
0006-4329-03
11-Digit CMS (5-4-2)
00006-4329-03

Note: The zero is added to the Labeler segment to maintain the 5-4-2 structure.