Isopto Atropine Solution
Pricing Report NDC 0065-0303-55

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The latest wholesale acquisition cost for Isopto Atropine (NDC 0065-0303-55) is $10.37984 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Feb 07, 2023.

As a a human prescription drug provided by Alcon Laboratories, Inc., this medication is distributed in a 1 BOTTLE, DROPPER in 1 CARTON / 5 mL in 1 BOTTLE, DROPPER configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$10.37984
Per ML

Pricing Unit
Per ML Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Feb 07, 2023
Data Status
As of May 24, 2023
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
B - Brand
Package NDC
0065-0303-55
Description
1 BOTTLE, DROPPER in 1 CARTON / 5 mL in 1 BOTTLE, DROPPER
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Dec 2018, the NADAC wholesale price for (NDC ) has moved within a range of $8.92200 to $10.37984 per ML. Over this 4 years and 1 month period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$8.9220 - $10.3798
Market Volatility
16.34% Variance
Latest Trend
6.99%
Date Unit Price Unit Source Method Rate
Feb 07, 2023 $10.37984 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Feb 07, 2023 $10.37984 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 17, 2022 $9.70133 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 17, 2022 $9.70133 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 17, 2022 $9.70133 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 20, 2022 $9.71756 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Apr 20, 2022 $9.71756 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Feb 23, 2022 $9.22089 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 01, 2022 $9.68249 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 01, 2022 $9.68249 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Apr 21, 2021 $9.23792 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 21, 2021 $9.23792 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2020 $9.23534 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2020 $9.23534 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Oct 23, 2019 $8.92200 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2019 $8.92200 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 19, 2018 $8.95167 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 19, 2018 $8.95167 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026