Systane Lubricant Solution/ Drops
Pricing Report NDC 0065-0429-21

Latest NADAC: $0.95116 per ML · Effective Mar 17, 2021

Current Package Pricing Information

The latest wholesale acquisition cost for Systane Lubricant (NDC 0065-0429-21) is $0.95116 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Mar 17, 2021.

As a a human over the counter drug provided by Alcon Laboratories, Inc., this medication is distributed in a 2 BOTTLE, DROPPER in 1 CARTON / 5 mL in 1 BOTTLE, DROPPER configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.95116
Per ML

Effective Date
Mar 17, 2021
Data Status
As of May 26, 2021
C/I - Chain or Independent Pharmacy
Package NDC
Description
2 BOTTLE, DROPPER in 1 CARTON / 5 mL in 1 BOTTLE, DROPPER
Pricing Methodology Explanation
The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Feb 2013, the NADAC wholesale price for (NDC ) has moved within a range of $0.44132 to $0.95532 per ML. Over this 13 years and 5 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.4413 - $0.9512
Market Volatility
115.53% Variance
Latest Trend
0.25%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 19, 2026 $0.69823 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Aug 19, 2026 $0.56727 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 22, 2026 $0.69998 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 22, 2026 $0.56488 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jun 17, 2026 $0.69953 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jun 17, 2026 $0.56320 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 20, 2026 $0.69893 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 20, 2026 $0.56298 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 22, 2026 $0.69500 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 22, 2026 $0.56045 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Mar 18, 2026 $0.69575 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Mar 18, 2026 $0.56115 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026