Systane Gel
Pricing Report NDC 0065-0454-07

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Systane (NDC 0065-0454-07) is $1.13244 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human over the counter drug provided by Alcon Laboratories, Inc., this medication is distributed in a 10 mL in 1 BOTTLE, DROPPER configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1.13244
Per ML

Effective Date
Jun 17, 2026
Billable Units
10 ML
Estimated Package Price
$11.32
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
10 mL in 1 BOTTLE, DROPPER
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2013, the NADAC wholesale price for (NDC ) has moved within a range of $0.89897 to $1.13899 per ML. Over this 12 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.8990 - $1.1390
Market Volatility
26.70% Variance
Latest Trend
0.15%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $1.13244 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 20, 2026 $1.13417 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 22, 2026 $1.13324 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Mar 18, 2026 $1.13483 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 18, 2026 $1.13579 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jan 21, 2026 $1.13637 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 17, 2025 $1.13738 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Nov 19, 2025 $1.13789 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 22, 2025 $1.13899 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Sep 17, 2025 $1.13635 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Aug 20, 2025 $1.13343 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 23, 2025 $1.13060 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jun 18, 2025 $1.12969 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 21, 2025 $1.12355 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 23, 2025 $1.12083 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Mar 19, 2025 $1.11385 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 19, 2025 $1.11005 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jan 22, 2025 $1.10726 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 18, 2024 $1.10166 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Nov 20, 2024 $1.09530 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 23, 2024 $1.08990 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Sep 18, 2024 $1.08742 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Aug 21, 2024 $1.08749 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 17, 2024 $1.08706 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jun 19, 2024 $1.08689 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 22, 2024 $1.08739 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 17, 2024 $1.08323 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 20, 2023 $1.08400 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 20, 2023 $1.08400 MLC/I - Chain or Independent PharmacyCode 4, 5, 6B - Brand
Oct 18, 2023 $1.07014 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 18, 2023 $1.07014 MLC/I - Chain or Independent PharmacyCode 4, 5, 6B - Brand
Sep 20, 2023 $1.10184 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 19, 2023 $1.07867 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 19, 2023 $1.07867 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Jun 21, 2023 $1.10758 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 22, 2023 $1.08200 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 22, 2023 $1.08200 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 22, 2023 $1.08200 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Jan 18, 2023 $1.10664 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jan 18, 2023 $1.10664 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 21, 2022 $1.06203 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 21, 2022 $1.06203 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Nov 23, 2022 $1.00660 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 19, 2022 $1.08773 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 20, 2022 $1.07157 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 20, 2022 $1.07157 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Jul 20, 2022 $1.07157 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
May 18, 2022 $1.04629 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 18, 2022 $1.04629 MLC/I - Chain or Independent PharmacyCode 4, 5, 6B - Brand
Sep 22, 2021 $1.00957 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Sep 22, 2021 $1.00957 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Nov 18, 2020 $1.01029 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Nov 18, 2020 $1.01029 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Sep 23, 2020 $0.97371 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Sep 23, 2020 $0.97371 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Aug 19, 2020 $0.99484 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 23, 2019 $0.97352 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 23, 2019 $0.97352 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Apr 17, 2019 $0.96500 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 17, 2019 $0.96500 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Jun 20, 2018 $0.97433 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jun 20, 2018 $0.97433 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Jun 20, 2018 $0.97433 MLC/I - Chain or Independent PharmacyCode 4, 5, 6B - Brand
Feb 21, 2018 $0.95020 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 21, 2018 $0.95020 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Oct 18, 2017 $0.97258 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 18, 2017 $0.97258 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Sep 20, 2017 $0.93831 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 17, 2017 $0.90261 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 17, 2017 $0.90261 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Apr 19, 2017 $0.92769 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jan 18, 2017 $0.89897 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jan 18, 2017 $0.89897 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Sep 21, 2016 $0.92069 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Sep 21, 2016 $0.92069 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Jul 20, 2016 $0.90090 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 20, 2016 $0.90090 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Jun 22, 2016 $0.90447 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 23, 2015 $0.92607 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 23, 2015 $0.92607 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Aug 19, 2015 $0.90096 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Aug 19, 2015 $0.90096 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Mar 18, 2015 $0.92012 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Mar 18, 2015 $0.92012 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Aug 20, 2014 $0.90109 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Aug 20, 2014 $0.90109 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Dec 18, 2013 $0.92417 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 18, 2013 $0.92417 MLC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Nov 21, 2013 $0.91765 MLC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026