Systane Hydration Pf Preservative Free Solution/ Drops
Pricing Report NDC 0065-1437-04

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Systane Hydration Pf Preservative Free (NDC 0065-1437-04) is $0.37362 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human over the counter drug provided by Alcon Laboratories, Inc., this medication is distributed in a 30 VIAL, SINGLE-DOSE in 1 CARTON / .7 mL in 1 VIAL, SINGLE-DOSE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.37362
Per EA

Effective Date
Jun 17, 2026
Billable Units
1 EA
Estimated Package Price
$0.37
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
30 VIAL, SINGLE-DOSE in 1 CARTON / .7 mL in 1 VIAL, SINGLE-DOSE
Generic Benchmark
The generic equivalent rate is $0.18658 (Effective: Jun 17, 2026)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2020, the NADAC wholesale price for (NDC ) has moved within a range of $0.32479 to $0.49000 per EA. Over this 6 years and 1 month period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.3248 - $0.4900
Market Volatility
50.87% Variance
Latest Trend
0.07%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.37362 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 20, 2026 $0.37336 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 22, 2026 $0.37492 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Mar 18, 2026 $0.37566 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jan 21, 2026 $0.49000 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jan 21, 2026 $0.49000 EAC/I - Chain or Independent PharmacyCode 4, 5, 6B - Brand
Dec 17, 2025 $0.48740 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 22, 2025 $0.37756 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 22, 2025 $0.37756 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Sep 17, 2025 $0.37502 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Aug 20, 2025 $0.37242 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 23, 2025 $0.37150 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jun 18, 2025 $0.37162 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 21, 2025 $0.37087 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 23, 2025 $0.36935 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Mar 19, 2025 $0.36639 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 19, 2025 $0.36704 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jan 22, 2025 $0.36489 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 18, 2024 $0.36443 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Nov 20, 2024 $0.36542 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 23, 2024 $0.36578 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Sep 18, 2024 $0.36566 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Aug 21, 2024 $0.36623 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 17, 2024 $0.37185 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jul 17, 2024 $0.37185 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jun 19, 2024 $0.36608 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jun 19, 2024 $0.36608 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 22, 2024 $0.36727 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 17, 2024 $0.37274 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Mar 20, 2024 $0.37240 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 21, 2024 $0.34566 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Nov 22, 2023 $0.37985 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Nov 22, 2023 $0.37985 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Sep 20, 2023 $0.36572 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Sep 20, 2023 $0.36572 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Aug 23, 2023 $0.37522 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 21, 2022 $0.36728 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 21, 2022 $0.36728 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Oct 19, 2022 $0.34038 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Oct 19, 2022 $0.34038 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Aug 17, 2022 $0.34986 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Aug 17, 2022 $0.34986 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Jul 20, 2022 $0.34847 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Jun 22, 2022 $0.34057 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 20, 2022 $0.36780 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Apr 20, 2022 $0.36780 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Mar 23, 2022 $0.34942 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 23, 2022 $0.33348 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 19, 2021 $0.34418 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 19, 2021 $0.34418 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
May 19, 2021 $0.34418 EAC/I - Chain or Independent PharmacyCode 4, 5, 6B - Brand
Apr 21, 2021 $0.33490 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 17, 2021 $0.34312 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Feb 17, 2021 $0.34312 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Jan 20, 2021 $0.40047 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Dec 23, 2020 $0.35261 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Sep 23, 2020 $0.33854 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
Sep 23, 2020 $0.33854 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
May 20, 2020 $0.32479 EAC/I - Chain or Independent PharmacyCode 1, 5, 6B - Brand
May 20, 2020 $0.32479 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand
Apr 29, 2020 $0.33362 EAC/I - Chain or Independent PharmacyCode 2, 5, 6B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026