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  5. NDC Package Code: 0065-4147-25 Simbrinza

NDC Package 0065-4147-25 Simbrinza

Brinzolamide/brimonidine Tartrate Suspension/ Drops Ophthalmic - View Billable Units, 11-Digit Format, RxNorm

Table of Contents

    1. Package Information
    2. Other Packages
    3. Frequently Asked Questions

Package Information

Find all the important details about this NDC Package code, including the 11-Digit NDC Billing number, billing units, wholesale price, RxNorm crosswalk, active ingredients, pharmacologic clasess, etc.

NDC Package Code:
0065-4147-25
Package Description:
1 BOTTLE, DROPPER in 1 CARTON / 2.5 mL in 1 BOTTLE, DROPPER
Product Code:
0065-4147
Proprietary Name:
Simbrinza
Non-Proprietary Name:
Brinzolamide/brimonidine Tartrate
Substance Name:
Brimonidine Tartrate; Brinzolamide
Usage Information:
This product contains two medications used to treat high pressure in the eye due to glaucoma (open-angle glaucoma-type) or a certain other eye disease (ocular hypertension). Lowering high pressure in the eye reduces the risk of vision loss, nerve damage, or blindness. This product contains brinzolamide and brimonidine. These two medications work together to decrease the amount of fluid within the eye. Brinzolamide belongs to a class of drugs known as carbonic anhydrase inhibitors. Brimonidine belongs to a class of drugs known as alpha agonists. This product is not recommended for use in children younger than 2 years of age due to an increased risk of serious side effects such as very slowed breathing. Ask the doctor or pharmacist for details.
11-Digit NDC Billing Format:
00065414725
NDC to RxNorm Crosswalk:
  • RxCUI: 1421451 - brinzolamide 1 % / brimonidine tartrate 0.2 % Ophthalmic Suspension
  • RxCUI: 1421451 - brimonidine tartrate 2 MG/ML / brinzolamide 10 MG/ML Ophthalmic Suspension
  • RxCUI: 1421451 - brimonidine tartrate 0.2 % / brinzolamide 1 % Ophthalmic Suspension
  • RxCUI: 1421456 - SIMBRINZA 1 % / 0.2 % Ophthalmic Suspension
  • RxCUI: 1421456 - brimonidine tartrate 2 MG/ML / brinzolamide 10 MG/ML Ophthalmic Suspension [Simbrinza]
    • Product Type:
    Human Prescription Drug
    Labeler Name:
    Alcon Laboratories, Inc.
    Dosage Form:
    Suspension/ Drops - A suspension which is usually administered in a dropwise fashion.
    Administration Route(s):
  • Ophthalmic - Administration to the external eye.
    • Active Ingredient(s):
  • BRIMONIDINE TARTRATE 2 mg/mL
  • BRINZOLAMIDE 10 mg/mL
    • Pharmacologic Class(es):
  • Adrenergic alpha-Agonists - [MoA] (Mechanism of Action)
  • Carbonic Anhydrase Inhibitor - [EPC] (Established Pharmacologic Class)
  • Carbonic Anhydrase Inhibitors - [MoA] (Mechanism of Action)
  • alpha-Adrenergic Agonist - [EPC] (Established Pharmacologic Class)
    • Sample Package:
    No
    FDA Application Number:
    NDA204251
    Marketing Category:
    NDA - A product marketed under an approved New Drug Application.
    Start Marketing Date:
    05-06-2013
    Listing Expiration Date:
    12-31-2024
    Exclude Flag:
    N
    Code Structure:

    The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

    * Please review the disclaimer below.

    Other Product Packages

    The following packages are also available for this product:

    NDC Package CodePackage Description
    0065-4147-271 BOTTLE, DROPPER in 1 CARTON / 8 mL in 1 BOTTLE, DROPPER

    * Please review the disclaimer below.

    Frequently Asked Questions

    What is NDC 0065-4147-25?

    The NDC Packaged Code 0065-4147-25 is assigned to a package of 1 bottle, dropper in 1 carton / 2.5 ml in 1 bottle, dropper of Simbrinza, a human prescription drug labeled by Alcon Laboratories, Inc.. The product's dosage form is suspension/ drops and is administered via ophthalmic form.

    Is NDC 0065-4147 included in the NDC Directory?

    Yes, Simbrinza with product code 0065-4147 is active and included in the NDC Directory. The product was first marketed by Alcon Laboratories, Inc. on May 06, 2013 and its listing in the NDC Directory is set to expire on December 31, 2024 if the product is not updated or renewed by the manufacturer.

    What is the 11-digit format for NDC 0065-4147-25?

    The 11-digit format is 00065414725. The 11-digit billing format might be required by the Centers for Medicare & Medicaid Services (CMS) and other payers in billing claim forms.

    This package code is originally configured in a 4-4-2 segment 10-digit format and by adding a zero within the original NDC package code we can obtain the converted 11-digit format in a 5-4-2 segment configuration. The table below shows the 11-digit code conversion:

    10-Digit Format10-Digit Original Code11-Digit Format11-Digit Code
    4-4-20065-4147-255-4-200065-4147-25