Suprane Liquid
Product Images NDC 0404-9961

Product Visual Gallery

This gallery contains 19 technical images submitted to the FDA as part of the official labeling for Suprane (NDC 0404-9961). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.

As provided by Henry Schein, Inc., these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.

FDA Label Image

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A line graph showing the relationship between partial pressure of carbon dioxide in arterial blood (PaCO2, mmHg) and minimum alveolar concentration (MAC) during spontaneous ventilation in unstimulated volunteers. The graph compares data for five inhalational agents: Desflurane, Enflurane, Isoflurane, Desflurane with Nitrous Oxide, and Halothane, with data points indicating mean values with standard error (SE). A note states that data for Enflurane, Halothane, and Isoflurane are from earlier studies.*

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A wash-in curve graph titled 'Desflurane Washin' showing the ratio of end-tidal to inspired anesthetic concentration (FA/FI) over time in minutes for four anesthetics: Nitrous Oxide, Desflurane, Isoflurane, and Halothane. The graph compares uptake in 8 normal male volunteers, with Nitrous Oxide reaching the highest FA/FI ratio most rapidly.*

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A line graph titled 'Figure 3. Desflurane Washout' depicting the mean and standard deviation of end-tidal anesthetic concentration ratios over time in minutes for 8 normal male volunteers. The x-axis represents time (0 to 150 minutes), and the y-axis represents the ratio of end-tidal anesthetic concentration (FA/FA0) on a logarithmic scale from 0.001 to 1. Three curves display washout data for Halothane, Isoflurane, and Desflurane, showing their relative anesthetic elimination over time.*

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Chemical structure of Desflurane, the active ingredient in Suprane. The diagram shows the molecular arrangement with fluorine, carbon, hydrogen, and oxygen atoms connected as part of the compound's formula.*

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This text panel lists adverse reactions associated with Suprane (Desflurane) occurring in less than 1% of patients. It categorizes events as probably causally related or of unknown causal relationship, reporting conditions across cardiovascular, digestive, nervous system, respiratory, metabolic, musculoskeletal, and skin systems from postmarketing experience and clinical trials.*

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A data table presenting physical constants and partition coefficients related to Suprane (Desflurane) at various temperatures. It includes molecular weight, specific gravity, vapor pressure at several temperatures, and partition coefficients for blood/gas, olive oil/gas, brain/gas, and mean component/gas for different materials such as polypropylene, polyethylene, latex rubber, and polyvinylchloride.*

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A data table titled 'Emergence and Recovery After Outpatient Laparoscopy' showing mean, standard deviation, and range of various recovery times in minutes for 178 females aged 20-47. The table compares four anesthetic induction and maintenance regimens involving Propofol and Desflurane with N2O or O2, presenting data for anesthetic time, time to open eyes, state name, stand, walk, and fit for discharge.*

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A data table presenting emergence and recovery times in outpatient surgery for 46 males and 42 females aged 19-70. It compares induction and maintenance anesthetic regimens including Thiopental with Isoflurane/N2O, Desflurane/N2O, Desflurane/O2, and Desflurane/O2 alone. Times measured include anesthetic time, time to open eyes, time to state name, time to walk, and time to fit for discharge, expressed as mean ± SD with ranges.*

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A data table titled 'Recovery Tests: Percent of Preoperative Baseline Values' showing mean ± SD percentages for 16 males and 22 females aged 20-65. It compares recovery parameters 60 and 90 minutes after anesthesia maintenance with Desflurane/N₂O versus Isoflurane/N₂O. Parameters include Confusion, Fatigue, Drowsiness, Clumsiness, Comfort, DSST+ score, and Trieger Tests with related footnotes for test definitions and statistical significance.*

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A data table titled 'Hemodynamic Effects of Desflurane During Controlled Ventilation' presenting mean ± SD and range values for heart rate, mean arterial pressure, and cardiac index in 12 male volunteers aged 16-26. The table compares these metrics across varying total MAC equivalents and gas mixtures of O2 and N2O during desflurane administration.*

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A data table titled 'Cardiovascular Patients by Agent and Type of Surgery' displaying the number of patients treated with different anesthetic agents across various surgery types. It includes patient counts for Isoflurane, Desflurane, Sufentanil, and Fentanyl from multiple centers, categorized by surgery such as CABG, Abd Aorta, Periph Vasc, and Carotid Art.*

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A data table showing respiratory events in nonintubated pediatric patients using Suprane (Desflurane) via face mask or LMA. The table presents percentages of various respiratory events — airway obstruction, breath-holding, coughing, laryngospasm, secretion, and non-specific desaturation — stratified by age groups (all ages, 2-6 years, 7-11 years, 12-16 years) with total patients noted in each group.*

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Table listing National Drug Codes (NDC) with container types and unit quantities. The containers shown are amber-colored glass and aluminum bottle options, each with unit counts of one or six.*

FDA Label Image

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Label for Suprane (Desflurane, USP) liquid for inhalation, 240 mL bottle. The label includes instructions to replace the cap after each use, notes it is a nonflammable, nonexplosive inhalation anesthetic, and advises storage at controlled room temperature between 59°F and 86°F. It shows Henry Schein, Inc. as the packager with address in Bastian, VA. The label is marked RX ONLY and contains a barcode and QR code along with placeholder text for lot number and expiration date.*

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A data table titled "Effect of Age on Minimum Alveolar Concentration of Desflurane" showing mean ± SD values (percent atmospheres) for different age groups under oxygen 100% and nitrogen oxide with oxygen (N2O 60%/40% O2) conditions. The table includes number of crossover pairs (N) and minimum alveolar concentration values for each age group ranging from 2 weeks to 70 years.*

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A table titled 'Frequency of Events Occurring in Greater Than 1% of Clinical Trial Patients (in Reports Deemed Probably Causally Related)' summarizing adverse events reported during induction and maintenance or recovery phases for adult and pediatric patients using Suprane (desflurane). Events include coughing, breathholding, apnea, increased secretions, and others categorized by body system such as cardiovascular, digestive, nervous, respiratory, and special senses with associated percentages and descriptions.*

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Table titled 'SUPRANE (desflurane, USP) MAC with Fentanyl or Midazolam' showing mean and standard deviation percent reduction in MAC for two age groups, 18-30 years and 31-65 years, at various doses of fentanyl and midazolam compared to no fentanyl or no midazolam.*

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A data table titled 'Dosage of Muscle Relaxant Causing 95% Depression in Neuromuscular Blockade' showing mean ED95 values (µg/kg) for Pancuronium, Atracurium, Succinylcholine, and Vecuronium at different Desflurane concentrations: 0.65 MAC 60% N2O/O2, 1.25 MAC 60% N2O/O2, and 1.25 MAC O2.*

FDA Label Image

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A table presenting recovery profiles comparing Desflurane 3% in N2O 60% versus Isoflurane 0.6% in N2O 60% in outpatients. It includes data on anesthetic time and recovery times such as following commands, sitting up, and fitness for discharge, reported as mean with standard deviation for 16 males and 22 females aged 20-65.*

* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.