Estradiol Transdermal System Patch
Product Images NDC 0781-7136

Product Visual Gallery

This gallery contains 20 technical images submitted to the FDA as part of the official labeling for Estradiol Transdermal System (NDC 0781-7136). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.

As provided by Sandoz Inc, these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.

FDA Label Image

0.025 Carton (Image 01)

Estradiol Transdermal System 0.025 mg/day patch packaging label. The label shows the product name and strength prominently with dosage form as a transdermal patch. It includes usage information, contents listing 2 mg estradiol per 6.5 cm² system, and storage warnings. The labeler Sandoz Inc is displayed at the bottom.*

FDA Label Image

0.0375 Carton (Image 02)

Estradiol Transdermal System 0.0375 mg/day patch label from Sandoz Inc. The label includes dosage strength and instructions indicating it is for transdermal use only, with four patches per package. It also notes inactive components and safety warnings to keep the drug out of reach of children.*

FDA Label Image

0.05 Carton (Image 03)

Estradiol Transdermal System 0.05 mg/day patch packaging label from Sandoz Inc. The label specifies it contains 4 transdermal systems, each delivering 0.05 mg of estradiol per day. It includes usage warnings for transdermal use only and instructions to keep out of reach of children.*

FDA Label Image

0.06 Carton (Image 04)

Estradiol Transdermal System 0.06 mg/day patch packaging label showing the product name, strength, dosage form as transdermal system, and labeler Sandoz Inc. The label includes usage instructions highlighting the active ingredient content per patch and warnings to keep out of reach of children. The package contains 4 transdermal systems.*

FDA Label Image

0.075 Carton (Image 05)

Estradiol Transdermal System 0.075 mg/day patch packaging label. The label states it is Rx only and contains 4 transdermal systems. It is manufactured by Sandoz Inc. The label notes that each system contains 5.7 mg estradiol USP to provide 0.075 mg estradiol per day with components including acrylic copolymer adhesive, fatty acids, and polyester/polyvinyl backing.*

FDA Label Image

0.1 Carton (Image 06)

Estradiol Transdermal System 0.1 mg/day patch packaging label by Sandoz Inc. The label states each 25 cm² system contains 7.6 mg estradiol USP to deliver 0.1 mg estradiol per day. It includes the Rx only designation and directions for transdermal use only. The package contains 4 transdermal systems.*

FDA Label Image

Chemical Structure (Image 07)

Chemical structure diagram of Estradiol, the active ingredient in the Estradiol Transdermal System by Sandoz Inc. The structure shows the four-ring steroid backbone characteristic of estradiol, including hydroxyl groups at specific positions.*

FDA Label Image

Protective Liner (Image 08)

An illustration showing the three layers of the Estradiol Transdermal System patch: (1) Film backing, (2) Drug/Adhesive layer, and (3) Protective liner. It visually represents the patch's layered structure for application.*

FDA Label Image

Figure 1 (Image 09)

A line graph showing concentration (pg/mL) over time (hours) for two sizes of Estradiol Transdermal System patches. The 6.5 cm² patch and the 12.5 cm² patch concentrations rise to peaks and then gradually decrease over 180 hours, with the 12.5 cm² patch showing higher concentrations throughout the time course.*

FDA Label Image

Figure 2 (Image 10)

A line graph depicting mean concentration (pg/mL) of Estradiol over time (hours) after patch application. The x-axis shows hours from 0 to 192, while the y-axis shows mean concentration from 0 to 200 pg/mL. Two lines compare sampling sites: buttock (solid line) and abdomen (dashed line), both peaking around 24-36 hours then gradually declining.*

FDA Label Image

Figure 3 (Image 11)

A line graph displaying percent change over time from baseline to 24 months. The x-axis represents visit times (baseline, 6, 12, 18, 24 months) and the y-axis shows percent change. Four treatment groups are plotted: placebo and three patch sizes (6.5 cm2, 12.5 cm2, 25 cm2), with placebo showing a decline and the patch groups showing varying increases over time.*

FDA Label Image

Figure 4 (Image 12)

A line graph displaying percent change over time from baseline to 24 months for different treatment groups, including placebo and three patch sizes (6.5 cm², 12.5 cm², 15 cm²). The x-axis represents visits at baseline, 6, 12, 18, and 24 months; the y-axis shows percent change. The graph compares treatment effects over time by patch size and placebo.*

FDA Label Image

Figure A (Image 13)

The image shows a packaging label for Estradiol Transdermal System. The label features the product name prominently and includes the labeler, Sandoz Inc, indicated as a Novartis Division. The label design includes a no-scissors symbol, suggesting no cutting of the patch.*

FDA Label Image

Figure B (Image 14)

An instructional illustration showing how to open the Estradiol Transdermal System patch packaging. The image highlights the side tear notch and bottom tear notch on the foil pouch and demonstrates a person's hands pulling the pouch apart at the side tear notch to access the patch inside.*

FDA Label Image

Figure C (Image 15)

An illustration of the Estradiol Transdermal System patch showing its two main components: the oval-shaped drug-containing patch labeled "Estradiol" and the surrounding protective backing. The patch is intended for transdermal delivery of estradiol.*

FDA Label Image

Figure D (Image 16)

An instructional illustration showing a person peeling away the protective backing from an Estradiol Transdermal System patch, preparing it for application to the skin.*

FDA Label Image

Figure E (Image 17)

An instructional illustration showing hands carefully removing an Estradiol Transdermal System patch from its packaging. The diagram emphasizes not removing the foil sticker while taking out the patch, providing a step-by-step visual guide for proper patch removal.*

FDA Label Image

Figure F (Image 18)

An instructional illustration showing the application of a transdermal patch to the lower abdomen of a person, demonstrating proper placement for a drug delivery system such as the Estradiol Transdermal System.*

FDA Label Image

Figure G (Image 19)

Illustration showing application of a transdermal patch to the buttock area. The hand is placing a small, square patch on the skin, indicating the proper site for applying the Estradiol Transdermal System patch.*

FDA Label Image

Figure H (Image 20)

An instructional illustration showing a hand applying a transdermal patch to the skin. The illustration depicts fingers pressing the patch onto the skin surface, indicating proper placement and application technique.*

* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.