Adapalene And Benzoyl Peroxide Gel, 0.1%/2.5% Gel
Pricing Report NDC 21922-052-50

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Adapalene And Benzoyl Peroxide Gel, 0.1%/2.5% (NDC 21922-052-50) is $0.29163 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Encube Ethicals, Inc., this medication is distributed in a 1 BOTTLE, PUMP in 1 CARTON / 45 g in 1 BOTTLE, PUMP configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.29163
Per GM

Effective Date
Jun 17, 2026
Billable Units
45 GM
Estimated Package Price
$13.12
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 BOTTLE, PUMP in 1 CARTON / 45 g in 1 BOTTLE, PUMP
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Dec 2023, the NADAC wholesale price for (NDC ) has moved within a range of $0.28528 to $0.72749 per GM. Over this 2 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.2853 - $0.7275
Market Volatility
155.01% Variance
Latest Trend
1.15%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.29163 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.29501 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.30375 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.28528 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.30037 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.31355 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.35185 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.37527 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.40156 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.41907 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.44454 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.45490 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.44431 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.42049 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.42833 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.47256 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.49741 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.55683 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.56217 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.65309 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.55316 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.63824 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.54151 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.48863 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.59291 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.44739 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.47382 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $0.72749 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $0.54728 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $0.58054 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.56647 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 13, 2023 $0.65188 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026