Aplisol Injection
Pricing Report NDC 42023-104-05
View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Current Package Pricing Information
The latest wholesale acquisition cost for Aplisol (NDC 42023-104-05) is $93.14573 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jan 02, 2026.
As a a human prescription drug provided by Endo Usa, Inc., this medication is distributed in a 1 VIAL in 1 CARTON / 5 mL in 1 VIAL configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.
NADAC Pricing Summary
NADAC pricing snapshot for this package NDC
Acquisition Cost $93.14573 Per ML
Pricing Unit
Effective Date
Jan 02, 2026
Data Status
As of Jul 08, 2026
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.
The NADAC was calculated based on package size.
Historical Pricing Trends & Acquisition Cost Benchmarks
Since Oct 2013, the NADAC wholesale price for (NDC ) has moved within a range of $27.24575 to $120.83968 per ML. Over this 12 years and 7 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.
Price Range
$27.2458 - $120.8397
$27.2458 - $120.8397
Market Volatility
343.52% Variance
343.52% Variance
Latest Trend
0.35%
0.35%
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Jun 17, 2026 | $120.41757 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 20, 2026 | $120.83968 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 02, 2026 | $120.38151 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 02, 2026 | $120.38151 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 02, 2026 | $120.38151 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 02, 2026 | $93.14573 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 02, 2026 | $93.14573 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 02, 2026 | $93.14573 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Dec 17, 2025 | $110.43871 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 17, 2025 | $85.45480 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 19, 2025 | $109.70773 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 07, 2025 | $108.50281 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 07, 2025 | $108.50281 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 07, 2025 | $108.50281 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jul 07, 2025 | $85.86576 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 07, 2025 | $85.86576 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Feb 24, 2025 | $103.33699 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Feb 24, 2025 | $103.33699 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Feb 24, 2025 | $103.33699 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Feb 24, 2025 | $81.77614 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Feb 24, 2025 | $81.77614 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Feb 24, 2025 | $81.77614 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Feb 19, 2025 | $89.94037 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Feb 19, 2025 | $70.82086 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 22, 2025 | $89.89296 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 18, 2024 | $89.78371 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 18, 2024 | $68.01080 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 18, 2024 | $68.01080 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Nov 20, 2024 | $89.86796 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 23, 2024 | $89.81805 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Sep 18, 2024 | $89.68179 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 06, 2024 | $89.67414 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| May 06, 2024 | $89.67414 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| May 06, 2024 | $89.67414 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| May 06, 2024 | $68.80069 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| May 06, 2024 | $68.80069 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| May 06, 2024 | $68.80069 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Apr 17, 2024 | $83.02854 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Apr 17, 2024 | $63.70493 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 22, 2023 | $84.39750 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 22, 2023 | $84.39750 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Nov 22, 2023 | $84.39750 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Aug 23, 2023 | $82.51900 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 23, 2023 | $82.51900 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 19, 2023 | $84.60600 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 17, 2023 | $81.06800 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 17, 2023 | $81.06800 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 18, 2023 | $82.98600 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 18, 2023 | $82.98600 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 18, 2023 | $82.98600 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Aug 17, 2022 | $85.87143 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 17, 2022 | $85.87143 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Aug 17, 2022 | $85.87143 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 22, 2022 | $84.59833 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 22, 2022 | $84.59833 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jun 23, 2021 | $81.61833 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 23, 2021 | $81.61833 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jun 23, 2021 | $81.61833 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| May 20, 2020 | $83.62400 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 20, 2020 | $83.62400 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| May 20, 2020 | $83.62400 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Oct 23, 2019 | $85.45200 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 23, 2019 | $85.45200 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Nov 21, 2018 | $84.76020 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Nov 21, 2018 | $84.76020 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Nov 21, 2018 | $84.76020 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Oct 17, 2018 | $81.04756 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Oct 01, 2018 | $83.21250 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Oct 01, 2018 | $64.38727 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Oct 01, 2018 | $64.38727 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 17, 2018 | $75.99037 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 17, 2018 | $75.99037 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 17, 2018 | $75.99037 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Dec 20, 2017 | $77.68329 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 01, 2017 | $75.35489 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Dec 01, 2017 | $58.80116 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Dec 01, 2017 | $58.80116 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Sep 20, 2017 | $68.56429 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Sep 20, 2017 | $68.56429 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 19, 2017 | $65.41556 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 19, 2017 | $65.41556 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Apr 19, 2017 | $68.88667 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Apr 19, 2017 | $68.88667 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 03, 2017 | $68.52027 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 03, 2017 | $68.52027 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 03, 2017 | $68.52027 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 03, 2017 | $53.50472 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 03, 2017 | $53.50472 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Nov 23, 2016 | $62.86667 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 23, 2016 | $62.86667 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Oct 19, 2016 | $61.61944 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 17, 2016 | $64.54335 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Aug 17, 2016 | $64.54335 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jul 12, 2016 | $62.99608 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 12, 2016 | $49.08690 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 12, 2016 | $49.08690 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 20, 2016 | $57.79616 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 20, 2016 | $57.79616 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2016 | $58.72920 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2016 | $45.03385 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2016 | $45.03385 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Dec 23, 2015 | $53.88000 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 21, 2015 | $50.48143 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 21, 2015 | $50.48143 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Sep 23, 2015 | $52.87625 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 01, 2015 | $52.76849 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 01, 2015 | $52.76849 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 01, 2015 | $41.31546 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 01, 2015 | $41.31546 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 17, 2015 | $43.51071 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 20, 2015 | $43.13818 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Mar 18, 2015 | $45.44600 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Mar 18, 2015 | $45.44600 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Feb 18, 2015 | $42.60104 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2015 | $44.17485 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 01, 2015 | $44.17485 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2015 | $31.97742 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 01, 2015 | $31.97742 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2015 | $31.97742 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Dec 17, 2014 | $41.26100 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 17, 2014 | $28.77867 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 19, 2014 | $38.57846 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 22, 2014 | $39.67400 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 20, 2014 | $37.29100 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 20, 2014 | $37.29100 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Aug 20, 2014 | $27.92080 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 20, 2014 | $27.92080 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 18, 2014 | $39.05143 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 18, 2014 | $39.05143 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| May 21, 2014 | $40.11545 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 21, 2014 | $29.34960 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 21, 2014 | $29.34960 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Mar 19, 2014 | $35.83588 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Mar 19, 2014 | $35.83588 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Feb 19, 2014 | $39.70288 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2014 | $40.14176 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2014 | $28.33531 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 01, 2014 | $28.33531 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 01, 2014 | $28.33531 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Nov 21, 2013 | $39.45034 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 21, 2013 | $39.45034 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Oct 24, 2013 | $27.24575 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
Pricing Methodology Legend
- Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
- Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
- Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
- Code 4: The NADAC was carried forward from the previous file.
- Code 5: The NADAC was calculated based on package size.
Understanding NADAC Pricing Data
The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.
Important Price Distinction:
The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.
NADAC Pricing Data Last Updated on: July 08, 2026
