Nereus Capsule
NDC Package 43068-585-01

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Other Packages
    3. Frequently Asked Questions

Package Information

Nereus (tradipitant) capsules is nEREUS is indicated for the prevention of vomiting induced by motion in adults. This formulation utilizes a capsule delivery system. Marketed by Vanda Pharmaceuticals Inc., this product is identified by NDC 43068-585 and is authorized under FDA application NDA220152.

Identification & Billing

NDC Package Code
43068-585-01
Package Description
60 CARTON in 1 BOTTLE / 1 CAPSULE in 1 CARTON
Product Code
43068-585
11-Digit Billing Format
43068058501
Billing Unit
EA - Billing unit of "each" is used when the product is dispensed in discreet units.
Units Per Package
60 EA
RxNorm Crosswalk

Clinical Specifications

Proprietary Name
Nereus
Non-Proprietary Name
Tradipitant
Substance Name
Tradipitant
Dosage Form
Capsule - A solid oral dosage form consisting of a shell and a filling. The shell is composed of a single sealed enclosure, or two halves that fit together and which are sometimes sealed with a band. Capsule shells may be made from gelatin, starch, or cellulose, or other suitable materials, may be soft or hard, and are filled with solid or liquid ingredients that can be poured or squeezed.
Administration Route
Oral - Administration to or by way of the mouth.
Active Ingredient(s)
TRADIPITANT 85 mg/1
Usage Information
NEREUS is indicated for the prevention of vomiting induced by motion in adults.

Regulatory & Marketing

Labeler Name
Vanda Pharmaceuticals Inc.
Product Type
Human Prescription Drug
FDA Application #
NDA220152
Marketing Category
NDA - A product marketed under an approved New Drug Application.
Start Marketing Date
03-31-2026
Listing Expiration
12-31-2027
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Other Available Packages

The following commercial packages are registered under the same Product NDC (43068-585). Click a package code to view its specific billing and regulatory data.

43068-585-02
36 CARTON in 1 BOTTLE / 1 CAPSULE in 1 CARTON

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 43068-585-01 identifies a specific commercial package of 60 carton in 1 bottle / 1 capsule in 1 carton of Nereus, a human prescription drug labeled by Vanda Pharmaceuticals Inc.. This product is billed for "EA" each discreet unit and contains an estimated amount of 60 billable units per package. This capsule is formulated for oral use and contains tradipitant as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Vanda Pharmaceuticals Inc. on March 31, 2026. The current certification is valid through December 31, 2027.

How is this Vanda Pharmaceuticals Inc. product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 43068058501. Quantities are measured in per "each", products billed on a per each basis are usually products dispensed in discreet units.. There are 60 total billable units per package. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
43068-585-01
11-Digit CMS (5-4-2)
43068-0585-01

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.