Rebif Injection, Solution
Pricing Report NDC 44087-0022-3

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The latest wholesale acquisition cost for Rebif (NDC 44087-0022-3) is $1400.93426 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jan 15, 2021.

As a a human prescription drug provided by Emd Serono, Inc., this medication is distributed in a 12 SYRINGE, GLASS in 1 CARTON / .5 mL in 1 SYRINGE, GLASS (44087-0022-9) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1,400.93426
Per ML

Pricing Unit
Per ML Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Jan 15, 2021
Data Status
As of Jan 12, 2022
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
B - Brand
Package NDC
44087-0022-3
Description
12 SYRINGE, GLASS in 1 CARTON / .5 mL in 1 SYRINGE, GLASS (44087-0022-9)
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jan 2014, the NADAC wholesale price for (NDC ) has moved within a range of $763.54398 to $1,400.93426 per ML. Over this 6 years and 11 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$763.5440 - $1,400.9343
Market Volatility
83.48% Variance
Latest Trend
6.00%
Date Unit Price Unit Source Method Rate
Jan 15, 2021 $1400.93426 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 15, 2021 $1400.93426 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 03, 2020 $1321.63610 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Apr 03, 2020 $1321.63610 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Sep 26, 2019 $1258.70104 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Sep 26, 2019 $1258.70104 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 11, 2019 $1201.05062 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 11, 2019 $1201.05062 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 01, 2018 $1149.33073 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Feb 01, 2018 $1149.33073 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 02, 2017 $1085.29814 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Aug 02, 2017 $1085.29814 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 06, 2017 $1046.57487 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 06, 2017 $1046.57487 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 01, 2016 $992.01410 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2016 $992.01410 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 12, 2016 $944.77533 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 12, 2016 $944.77533 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Sep 04, 2015 $909.31216 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Sep 04, 2015 $909.31216 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 20, 2015 $857.84166 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Feb 20, 2015 $857.84166 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 03, 2014 $816.99206 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Oct 03, 2014 $816.99206 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 22, 2014 $763.54398 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 22, 2014 $763.54398 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand

Pricing Methodology Legend

  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026