NDC 47426-401 Aponvie
Aprepitant Emulsion Intravenous
NDC Code 47426-401-10
Package Description: 10 VIAL, GLASS in 1 CARTON / 4.4 mL in 1 VIAL, GLASS (47426-401-01)
What is NDC 47426-401?
The NDC code 47426-401 is assigned by the FDA to the product Aponvie which is a human prescription drug product labeled by Heron Therapeutics, Inc.. The generic name of Aponvie is aprepitant. The product's dosage form is emulsion and is administered via intravenous form. The product is distributed in a single package with assigned NDC code 47426-401-10 10 vial, glass in 1 carton / 4.4 ml in 1 vial, glass (47426-401-01). This page includes all the important details about this product, including active and inactive ingredients, pharmagologic classes, product uses and characteristics, UNII information and RxNorm crosswalk.
What are the uses for Aponvie?
Aprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). Aprepitant works by blocking one of the body's natural substances (substance P/neurokinin 1) that causes vomiting. This medication will not treat nausea or vomiting that has already started. Ask your doctor what you should do if you already have nausea or vomiting.
What are Aponvie Active Ingredients?
An active ingredient is the substance responsible for the medicinal effects of a product specified by the substance's molecular structure or if the molecular structure is not known, defined by an unambiguous definition that identifies the substance. Each active ingredient name is the preferred term of the UNII code submitted.
- APREPITANT 32 mg/4.4mL - A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevention of POSTOPERATIVE NAUSEA AND VOMITING.
Which are Aponvie UNII Codes?
The UNII codes for the active ingredients in this product are:
- APREPITANT (UNII: 1NF15YR6UY)
- APREPITANT (UNII: 1NF15YR6UY) (Active Moiety)
What is the NDC to RxNorm Crosswalk for Aponvie?
RxNorm is a normalized naming system for generic and branded drugs that assigns unique concept identifier(s) known as RxCUIs to NDC products.The NDC to RxNorm Crosswalk for this produdct indicates multiple concept unique identifiers (RXCUIs) are associated with this product:
- RxCUI: 2631783 - aprepitant 32 MG in 4.4 ML Injection
- RxCUI: 2631783 - 4.4 ML aprepitant 7.2 MG/ML Injection
- RxCUI: 2631783 - aprepitant 32 MG per 4.4 ML Injection
- RxCUI: 2631788 - APONVIE 32 MG in 4.4 ML Injection
- RxCUI: 2631788 - 4.4 ML aprepitant 7.2 MG/ML Injection [Aponvie]
Which are Aponvie Inactive Ingredients UNII Codes?
The inactive ingredients are all the component of a medicinal product OTHER than the active ingredient(s). The acronym "UNII" stands for “Unique Ingredient Identifier” and is used to identify each inactive ingredient present in a product. The UNII codes for the inactive ingredients in this product are:
- EGG PHOSPHOLIPIDS (UNII: 1Z74184RGV)
- ALCOHOL (UNII: 3K9958V90M)
- SODIUM OLEATE (UNII: 399SL044HN)
- SOYBEAN OIL (UNII: 241ATL177A)
- SUCROSE (UNII: C151H8M554)
- WATER (UNII: 059QF0KO0R)
Which are the Pharmacologic Classes for Aponvie?
A pharmacologic class is a group of drugs that share the same scientifically documented properties. The following is a list of the reported pharmacologic class(es) corresponding to the active ingredients of this product.
- Cytochrome P450 2C9 Inducers - [MoA] (Mechanism of Action)
- Cytochrome P450 3A4 Inducers - [MoA] (Mechanism of Action)
- Cytochrome P450 3A4 Inhibitors - [MoA] (Mechanism of Action)
- Neurokinin 1 Antagonists - [MoA] (Mechanism of Action)
- Substance P/Neurokinin-1 Receptor Antagonist - [EPC] (Established Pharmacologic Class)
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